Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

…, P Tuluc, J Zhou, MV Clausen, A Lieb, C Maniero… - Nature …, 2013 - nature.com
At least 5% of individuals with hypertension have adrenal aldosterone-producing adenomas
(APAs). Gain-of-function mutations in KCNJ5 and apparent loss-of-function mutations in …

Prevalence, Clinical, and Molecular Correlates of KCNJ5 Mutations in Primary Aldosteronism

…, K Lang, H Lefebvre, L Lenzini, C Maniero… - …, 2012 - Am Heart Assoc
Primary aldosteronism is the most common form of secondary hypertension. Mutations in
the KCNJ5 gene have been described recently in aldosterone-producing adenomas (APAs). …

Mild hyperparathyroidism: a novel surgically correctable feature of primary aldosteronism

C Maniero, A Fassina, TM Seccia, A Toniato… - Journal of …, 2012 - journals.lww.com
Background: The parathyroid hormone (PTH) stimulates aldosterone secretion and cell
proliferation in human adrenocortical cells; moreover, in rats hyperaldosteronism was associated …

Primary hyperparathyroidism with concurrent primary aldosteronism

C Maniero, A Fassina, V Guzzardo, L Lenzini… - …, 2011 - Am Heart Assoc
Primary aldosteronism (PA) is a common cause of second-ary hypertension, because it involves
11.2% of referred hypertensive patients. 1 Primary hyperparathyroidism (PPTH) is much …

Current Perspectives on Coronavirus Disease 2019 and Cardiovascular Disease: A White Paper by the JAHA Editors

…, J Gutierrez, DA Jones, V Kapil, C Maniero… - Journal of the …, 2020 - Am Heart Assoc
Coronavirus Disease 2019 (COVID‐19) has infected more than 3.0 million people worldwide
and killed more than 200,000 as of April 27, 2020. In this White Paper, we address the …

Hyperparathyroidism can be useful in the identification of primary aldosteronism due to aldosterone-producing adenoma

GP Rossi, F Ragazzo, TM Seccia, C Maniero… - …, 2012 - Am Heart Assoc
Hyperparathyroidism represents as a novel feature of primary aldosteronism (PA). Its occurrence
in patients with the surgically correctable aldosterone-producing adenoma (APA) and …

Drug-related hypertension and resistance to antihypertensive treatment: a call for action

GP Rossi, TM Seccia, C Maniero… - Journal of …, 2011 - journals.lww.com
Several drugs can cause hypertension and/or blunt the effect of antihypertensive treatment.
They can exacerbate a previously well controlled hypertension and/or render it resistant to …

Non-pharmacological factors for hypertension management: a systematic review of international guidelines

C Maniero, A Lopuszko, KB Papalois… - European journal of …, 2023 - academic.oup.com
Lifestyle modifications are one of the cornerstones of hypertension prevention and treatment.
We aimed to systematically review hypertension guidelines on their recommendations on …

A stress reaction affects assessment of selectivity of adrenal venous sampling and of lateralization of aldosterone excess in primary aldosteronism

…, R Motta, M Barisa, C Maniero… - European journal of …, 2012 - academic.oup.com
Background A stress reaction involving increased cortisol release, which has not been
documented thus far, might affect the assessment of selectivity of catheterization during adrenal …

Longitudinal comparisons of mental health, burnout and well-being in patient-facing, non-patient-facing healthcare professionals and non-healthcare professionals …

V Kapil, G Collett, T Godec, J Gupta, C Maniero… - BJPsych Open, 2022 - cambridge.org
Background The COVID-19 pandemic may disproportionately affect the mental health of
healthcare professionals (HCPs), especially patient-facing HCPs. Aims To longitudinally …