Rationale Animal studies have found robust sex differences in the pharmacokinetics and
pharmacodynamics of Δ 9 -tetrahydrocannabinol (THC). However, the human evidence …

To characterize prescription opioid dependent patients in a methadone maintenance treatment
(MMT) program, a detailed retrospective chart review of new admissions (1997–1999, n=…

Background Although driving under the influence of cannabis is increasingly common among
young adults, little is known about residual effects on driver behavior. This study examined …

The road safety impact of cannabis has been a topic of much discussion and debate over
the years. These discussions have been revitalized in recent years by initiatives in several …

Anxiety disorders have the highest lifetime prevalence of any mental illness worldwide,
leading to high societal costs and economic burden. Current pharmacotherapies for anxiety …

Supervised methadone consumption is an important part of methadone maintenance treatment
(MMT) but may contribute to stigma for clients. Data from qualitative interviews with MMT …

The purposes of this study were to examine predictors of benzodiazepine use among
methadone maintenance treatment patients, to determine whether baseline benzodiazepine use …

OBJECTIVE To evaluate the clinical observation that the number of individuals seeking
opioid detoxification from oxycodone was increasing at the Centre for Addiction and Mental …

Background: Δ9-Tetrahydrocannabinol (THC) is the psychoactive component in cannabis
and a relationship of THC to driving impairment is expected. Despite this, there are discrepant …

The efficacy of naltrexone as a treatment for concurrent alcohol abuse or dependence and
pathological gambling was evaluated in a randomized, double‐blind, placebo‐controlled trial. …