Active inflammatory bowel disease (IBD) is often associated with simultaneous inflammation
in the skin, eyes and joints. Inflammatory disease in the liver can also occur in patients with …

Objective To summarize the relationship between obesity and remission in rheumatoid
arthritis (RA); secondary objectives were to summarize other measures of treatment response …

Primary sclerosing cholangitis (PSC) is a chronic cholangiopathy characterized by biliary
fibrosis, development of cholestasis and end stage liver disease, high risk of malignancy, and …

Normal intestinal mucosa contains abundant immunoglobulin A (IgA)–secreting cells, which
are generated from B cells in gut-associated lymphoid tissues (GALT). We show that …

A functionally distinct subset of CD103 + dendritic cells (DCs) has recently been identified in
murine mesenteric lymph nodes (MLN) that induces enhanced FoxP3 + T cell differentiation…

Background & Aims Primary sclerosing cholangitis (PSC) is an orphan hepatobiliary
disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of …

Primary sclerosing cholangitis (PSC) is a severe liver disease of unknown etiology leading to
fibrotic destruction of the bile ducts and ultimately to the need for liver transplantation 1 , 2 , …

Primary sclerosing cholangitis (PSC), a chronic inflammatory liver disease characterized by
progressive bile duct destruction, develops as an extra-intestinal complication of …

Primary sclerosing cholangitis (PSC) is a rare progressive disorder leading to bile duct
destruction; ∼75% of patients have comorbid inflammatory bowel disease (IBD). We undertook …

Regulatory T cells (T regs) are found at sites of chronic inflammation where they mediate
bystander and Ag-specific suppression of local immune responses. However, little is known …