Background Aiming at therapeutic targets has reduced the risk of organ failure in many
diseases such as diabetes or hypertension. Such targets have not been defined for rheumatoid …

Background Reaching the therapeutic target of remission or low-disease activity has
improved outcomes in patients with rheumatoid arthritis (RA) significantly. The treat-to-target …

Objective To evaluate the safety and efficacy of long‐term intraarticular (IA) steroid injections
for knee pain related to osteoarthritis (OA). Methods In a randomized, double‐blind trial, 68 …

The objective of this systematic literature review was to determine the association between
cardiovascular events (CVEs) and antirheumatic drugs in rheumatoid arthritis (RA) and …

Background: The relation between knee meniscal structural damage and cartilage degradation
is plausible but not yet clearly proven. Objectives: To quantitate the cartilage volume …

Objective. To compare the relative efficacy and tolerability of amitriptyline, cyclobenzaprine,
and placebo in the treatment of fibromyalgia, and to identify predictors of response to …

Objective To evaluate the change in osteoarthritic (OA) knee cartilage volume over a two‐year
period with the use of magnetic resonance imaging (MRI) and to correlate the MRI …

Objective. The Canadian Rheumatology Association (CRA) has developed recommendations
for the pharmacological management of rheumatoid arthritis (RA) with traditional and …

Objective To review published cases of induced or exacerbated interstitial lung disease (ILD)
in rheumatoid arthritis (RA) associated with non-biologic disease-modifying antirheumatic …

Objective To evaluate the efficacy and safety of diacerein, a drug with interleukin‐1β–inhibitory
activity in vitro, in patients with knee osteoarthritis (OA). Methods A total of 484 patients …