Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
The recent abundance of genome sequence data has brought an urgent need for systematic
proteomics to decipher the encoded protein networks that dictate cellular function 1 . To …
proteomics to decipher the encoded protein networks that dictate cellular function 1 . To …
β-Catenin mutations are specific for colorectal carcinomas with microsatellite instability but occur in endometrial carcinomas irrespective of mutator pathway
L Mirabelli-Primdahl, R Gryfe, H Kim, A Millar, C Luceri… - Cancer research, 1999 - AACR
Some colorectal tumors with wild-type adenomatous polyposis coli gene have activating
mutations in β-catenin (encoded by CTNNB1) that result in decreased phosphorylation by GSK-…
mutations in β-catenin (encoded by CTNNB1) that result in decreased phosphorylation by GSK-…
Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors
…, R Gryfe, H Kim, K So, A Millar… - The American journal …, 1999 - journals.lww.com
Inactivation of deoxyribonucleic acid (DNA) mismatch repair genes, most commonly human
mutL homologue 1 (hMLH1) or human mutS homologue 2 (hMSH2), is a recently described …
mutL homologue 1 (hMLH1) or human mutS homologue 2 (hMSH2), is a recently described …
Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability
V Vassileva, A Millar, L Briollais, W Chapman, B Bapat - Cancer research, 2002 - AACR
Microsatellite instability (MSI) is observed in a subset of endometrial cancers (ECs) and is
attributed to defects in mismatch repair. Mismatch repair deficiency allows for accumulation of …
attributed to defects in mismatch repair. Mismatch repair deficiency allows for accumulation of …
[HTML][HTML] Development of a core outcome set for effectiveness trials aimed at optimising prescribing in older adults in care homes
AN Millar, A Daffu-O'Reilly, CM Hughes, DP Alldred… - Trials, 2017 - Springer
Background Prescribing medicines for older adults in care homes is known to be sub-optimal.
Whilst trials testing interventions to optimise prescribing in this setting have been published…
Whilst trials testing interventions to optimise prescribing in this setting have been published…
Methylation of Adenomatous Polyposis Coli in Endometrial Cancer Occurs More Frequently in Tumors with Microsatellite Instability Phenotype
M Zysman, A Saka, A Millar, J Knight, W Chapman… - Cancer research, 2002 - AACR
Differential methylation is an important epigenetic control mechanism, which has been implicated
in the development of a variety of cancers. Methylation of promoter regions of normally …
in the development of a variety of cancers. Methylation of promoter regions of normally …
Mismatch repair gene defects contribute to the genetic basis of double primary cancers of the colorectum and endometrium
AL Millar, T Pal, L Madlensky, C Sherman… - Human molecular …, 1999 - academic.oup.com
Hereditary non-polyposis colorectal cancer (HNPCC) is a dominantly inherited cancer syndrome
caused by germline defects of mismatch repair (MMR) genes. Endometrial cancer is the …
caused by germline defects of mismatch repair (MMR) genes. Endometrial cancer is the …
[HTML][HTML] The Care Home Independent Prescribing Pharmacist Study (CHIPPS)—a non-randomised feasibility study of independent pharmacist prescribing in care …
…, J Ford, CM Hughes, V Maskrey, A Millar… - Pilot and feasibility …, 2019 - Springer
Background Residents in care homes are often very frail, have complex medicine regimens
and are at high risk of adverse drug events. It has been recommended that one healthcare …
and are at high risk of adverse drug events. It has been recommended that one healthcare …
[HTML][HTML] Evaluating the prevalence of potentially inappropriate prescribing in older adults in intermediate care facilities: a cross-sectional observational study
A Millar, C Hughes, C Ryan - International journal of clinical pharmacy, 2017 - Springer
Background Potentially inappropriate prescribing (PIP) [encompassing potentially inappropriate
medicines (PIMs) and potential prescribing omissions (PPOs)], is prevalent amongst …
medicines (PIMs) and potential prescribing omissions (PPOs)], is prevalent amongst …
Do MSH6 mutations contribute to double primary cancers of the colorectum and endometrium?
GS Charames, AL Millar, T Pal, S Narod, B Bapat - Human genetics, 2000 - Springer
Mismatch repair (MMR) gene mutations cause hereditary nonpolyposis colorectal cancer (HNPCC),
a common form of familial colorectal cancer. Among MMR genes, germline MSH6 …
a common form of familial colorectal cancer. Among MMR genes, germline MSH6 …