B-type natriuretic peptide in pediatrics

GK Davis, F Bamforth, A Sarpal, F Dicke, Y Rabi… - Clinical …, 2006 - Elsevier
OBJECTIVES:: There has been growing interest in the use of serum B-type natriuretic peptide
(BNP) and the N-terminal segment of its pro-hormone (NT-proBNP) as biomarkers for …

Effect of fresh vs standard-issue red blood cell transfusions on multiple organ dysfunction syndrome in critically ill pediatric patients: a randomized clinical trial

…, K Menon, JA Muszynski, ME Nellis, A Sarpal… - Jama, 2019 - jamanetwork.com
Importance The clinical consequences of red blood cell storage age for critically ill pediatric
patients have not been examined in a large, randomized clinical trial. Objective To …

Pediatric palliative care in Canada in 2012: a cross-sectional descriptive study

…, C Vadeboncoeur, S Liben, A Sarpal… - … Open Access Journal, 2016 - cmajopen.ca
Background: Pediatric palliative care focuses on comprehensive symptom management and
enhancing quality of life for children with life-threatening conditions and their families. Our …

Parental presence at the bedside of critically ill children in a unit with unrestricted visitation

…, T AlOfisan, YM AlGarni, A Sarpal - Pediatric Critical Care …, 2018 - journals.lww.com
Objectives: To determine the percentage of time that critically ill children have a parent at
the bedside and to identify extrinsic factors that are associated with percent of time with …

[HTML][HTML] Application of a gene modular approach for clinical phenotype genotype association and sepsis prediction using machine learning in meningococcal sepsis

…, J Brierley, M Uddin, H Alkhzaimi, A Sarpal… - Informatics in Medicine …, 2023 - Elsevier
Sepsis is a major global health concern causing high morbidity and mortality rates. Our
study utilized a Meningococcal Septic Shock (MSS) temporal dataset to investigate the …

[HTML][HTML] A Transcriptomic Appreciation of Childhood Meningococcal and Polymicrobial Sepsis from a Pro-Inflammatory and Trajectorial Perspective, a Role for …

…, H Alkhazaimi, J Sharief, R Kadwa, A Sarpal… - Shock, 2023 - journals.lww.com
This study investigated the temporal dynamics of childhood sepsis by analyzing gene
expression changes associated with proinflammatory processes. Five datasets, including four …

Advancing sepsis clinical research: harnessing transcriptomics for an omics-based strategy-a comprehensive scoping review

…, N Quraishi, R Kadwa, A Sarpal… - … in Medicine Unlocked, 2023 - mouseion.jax.org
Sepsis continues to be recognized as a significant global health challenge across all ages
and is characterized by a complex pathophysiology. In this scoping review, PRISMA-ScR …

[HTML][HTML] Perceived potentially inappropriate treatment in the PICU: frequency, contributing factors and the distress it triggers

A Sarpal, MR Miller, CM Martin, RW Sibbald… - Frontiers in …, 2024 - frontiersin.org
Background Potentially inappropriate treatment in critically ill adults is associated with
healthcare provider distress and burnout. Knowledge regarding perceived potentially …

[HTML][HTML] Applying transcriptomics for an enhanced clinical research framework, implications for an improved research strategy based on an omics approach: A scoping …

…, S Deshpande, N Quraishi, R Kadwa, A Sarpal… - Informatics in Medicine …, 2023 - Elsevier
Sepsis continues to be recognized as a significant global health challenge across all ages
and is characterized by a complex pathophysiology. In this scoping review, PRISMA-ScR …

VEGF subtype A and B Gene Expression, Clues to a Temporal Signature in Kawasaki Disease, Implications for Coronary Pathogenesis through a Secondary analysis …

…, ZA Malik, J Sharief, R Kadwa, BS Brusletto, A Sarpal… - medRxiv, 2022 - medrxiv.org
Background and Aim An essential issue for Kawasaki Disease (KD) is the development of
coronary artery disease. We decided to investigate (VEGF) subtype gene expression in KD …