Key points The maintenance of optimal mitochondrial content and function is critical for muscle
health. Mitochondrial dynamics play key roles in mitochondrial quality control; however, …

Insulin resistance due to overnutrition places a burden on energy-producing pathways in
skeletal muscle (SkM). Nevertheless, energy state is not compromised. The hypothesis that the …

BACKGROUND Familial hypercholesterolemia (FH), a common genetic condition, is
characterized by elevated low-density lipoprotein cholesterol (LDL-C) and premature …

… the data, Amanda Guerin, Iulia Iatan and Isabelle Ruel analyzed the data, and Amanda Guerin,
Iulia … Amanda Guerin and Iulia Iatan drafted the manuscript. All of the authors revised the …

… Genetic Disorders e53 Genetic Disorders 86 A Clinically Validated Genetic Screening for
Familial Hypercholesterolemia in Quebec Amanda Guerin, BSc, Jean-Baptiste Riviere, PhD, …

… Genetic Disorders 78 ^ Sex Disparities in the Treatment and Outcomes of Familial
Hypercholesterolemia Amanda Guerin, BSc (Montreal, QC) Lead Author’s Financial Disclosures: …

… Ngufor acquired the data; Amanda Guerin designed the plan of analysis. Amanda Guerin,
Iulia Iatan, … Amanda Guerin drafted the written work. Jacques Genest revised the written work. …

Obesity can lead to liver fibrosis and a selective insulin resistance whereby insulin-stimulated
lipogenesis is maintained and liver triglycerides (TG) are elevated, while insulin …

BACKGROUND Familial Hypercholesterolemia (FH) is the most common genetic disorder
in humans with an estimated prevalence of 1/311. In geographic regions with founder effect …

The human gut contains a vast array of viruses, mostly bacteriophages. The majority remain
uncharacterized, and their roles in shaping the gut microbiome and in impacting on human …