User profiles for Alfonso Iorio
Alfonso IorioProfessor and Chair, Department of Health Research Methods, Evidence, and Impact … Verified email at mcmaster.ca Cited by 30712 |
Interventions for enhancing medication adherence
…, T Agoritsas, N Mistry, A Iorio… - Cochrane database …, 2014 - cochranelibrary.com
Background People who are prescribed self administered medications typically take only
about half their prescribed doses. Efforts to assist patients with adherence to medications might …
about half their prescribed doses. Efforts to assist patients with adherence to medications might …
Discrimination and calibration of clinical prediction models: users' guides to the medical literature
Accurate information regarding prognosis is fundamental to optimal clinical care. The best
approach to assess patient prognosis relies on prediction models that simultaneously …
approach to assess patient prognosis relies on prediction models that simultaneously …
[HTML][HTML] The GRADE Working Group clarifies the construct of certainty of evidence
Objective To clarify the grading of recommendations assessment, development and evaluation
(GRADE) definition of certainty of evidence and suggest possible approaches to rating …
(GRADE) definition of certainty of evidence and suggest possible approaches to rating …
[HTML][HTML] d-Dimer Testing to Determine the Duration of Anticoagulation Therapy
Background The optimal duration of oral anticoagulation in patients with idiopathic venous
thromboembolism is uncertain. Testing of d-dimer levels may play a role in the assessment of …
thromboembolism is uncertain. Testing of d-dimer levels may play a role in the assessment of …
[HTML][HTML] Three months versus one year of oral anticoagulant therapy for idiopathic deep venous thrombosis
…, MG Santamaria, P Bagatella, A Iorio… - … England Journal of …, 2001 - Mass Medical Soc
Background In patients with idiopathic deep venous thrombosis, continuing anticoagulant
therapy beyond three months is associated with a reduced incidence of recurrent thrombosis …
therapy beyond three months is associated with a reduced incidence of recurrent thrombosis …
[HTML][HTML] Guideline for opioid therapy and chronic noncancer pain
…, C Cull, BR da Costa, JW Frank, G Grant, A Iorio… - Cmaj, 2017 - Can Med Assoc
Methods In developing this guideline, the steering committee followed standards for trustworthy
guidelines. 15 We included innovative approaches for key standards such as patient …
guidelines. 15 We included innovative approaches for key standards such as patient …
Aryl hydrocarbon receptor control of a disease tolerance defence pathway
Disease tolerance is the ability of the host to reduce the effect of infection on host fitness.
Analysis of disease tolerance pathways could provide new approaches for treating infections …
Analysis of disease tolerance pathways could provide new approaches for treating infections …
[HTML][HTML] Enoxaparin plus compression stockings compared with compression stockings alone in the prevention of venous thromboembolism after elective …
…, GC Andrioli, R Pugliese, A Iorio… - … England Journal of …, 1998 - Mass Medical Soc
Background Compression stockings are recommended for prophylaxis against venous
thromboembolism in patients undergoing neurosurgery, but anticoagulant agents have not …
thromboembolism in patients undergoing neurosurgery, but anticoagulant agents have not …
Use of GRADE for assessment of evidence about prognosis: rating confidence in estimates of event rates in broad categories of patients
The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE)
approach defines quality of evidence as confidence in effect estimates; this conceptualization …
approach defines quality of evidence as confidence in effect estimates; this conceptualization …
Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of …
…, G Günther, C Heller, S Holzhauer, A Iorio… - Circulation, 2010 - Am Heart Assoc
Background— The aim of this study was to estimate the impact of thrombophilia on risk of first
childhood stroke through a meta-analysis of published observational studies. Methods and …
childhood stroke through a meta-analysis of published observational studies. Methods and …