[HTML][HTML] Effect of genetics clinical decision support tools on health-care providers' decision making: a mixed-methods systematic review
Purpose Patient care involving genetics is challenging for nongenetics health-care providers.
Clinical decision support (CDS) tools are a potential solution because they provide patient-…
Clinical decision support (CDS) tools are a potential solution because they provide patient-…
“Game changer”: health professionals' views on the clinical utility of circulating tumor DNA testing in hereditary cancer syndrome management
…, M Clausen, C Mighton, A Sebastian… - The …, 2022 - academic.oup.com
Background We explored health professionals’ views on the utility of circulating tumor DNA (ctDNA)
testing in hereditary cancer syndrome (HCS) management. Materials and Methods A …
testing in hereditary cancer syndrome (HCS) management. Materials and Methods A …
Non-classical monocytes and its potential in diagnosing sepsis post cardiac surgery
A Sebastian, S Sanju, P Jain, VV Priya… - International …, 2021 - Elsevier
… Author links open overlay panel Agnes Sebastian a 1 , S. Sanju a 1 , Paresh Jain b , …
Agnes. S and S. Sanju were responsible for acquisition of data, analysis, interpretation of …
Agnes. S and S. Sanju were responsible for acquisition of data, analysis, interpretation of …
Use of real-world evidence in cancer drug funding decisions in Canada: A qualitative study of stakeholders' perspectives
M Clausen, C Mighton, R Kiflen, A Sebastian… - … Open Access Journal, 2020 - cmajopen.ca
Background: Real-world evidence (RWE) can provide postmarket data to inform whether
funded cancer drugs yield expected outcomes and value for money, but it is unclear how to …
funded cancer drugs yield expected outcomes and value for money, but it is unclear how to …
Widening the lens of actionability: a qualitative study of primary care providers' views and experiences of managing secondary genomic findings
A Sebastian, JC Carroll, M Vanstone… - European Journal of …, 2022 - nature.com
Most secondary genomic findings (SFs) fall in the scope of primary care practice. However,
primary care providers' (PCPs) capacity to manage these findings is not well understood. We …
primary care providers' (PCPs) capacity to manage these findings is not well understood. We …
Juridical analysis on the criminal act of online shop fraud in Indonesia
RK Karo, A Sebastian - Lentera Hukum, 2019 - HeinOnline
The development of technology has led to the sales and purchases of products and services
online. However, the absence of a physical store prevents the prospective buyers from …
online. However, the absence of a physical store prevents the prospective buyers from …
Challenges and practical solutions for managing secondary genomic findings in primary care
A Sebastian, JC Carroll, M Vanstone, M Clausen… - European Journal of …, 2022 - Elsevier
Primary care providers will increasingly be tasked with managing most secondary findings
from genomic sequencing, but literature exploring their capacity to manage findings beyond …
from genomic sequencing, but literature exploring their capacity to manage findings beyond …
How do members of the public expect to use variants of uncertain significance in their health care? A population-based survey
Purpose Genomic sequencing can generate complex results, including variants of uncertain
significance (VUS). In general, VUS should not inform clinical decision-making. This study …
significance (VUS). In general, VUS should not inform clinical decision-making. This study …
Great expectations: patients' preferences for clinically significant results from genomic sequencing
We aimed to describe patient preferences for a broad range of secondary findings (SF) from
genomic sequencing (GS) and factors driving preferences. We assessed preference data …
genomic sequencing (GS) and factors driving preferences. We assessed preference data …
Patient and public preferences for being recontacted with updated genomic results: a mixed methods study
Variants of uncertain significance (VUS) are frequently reclassified but recontacting patients
with updated results poses significant resource challenges. We aimed to characterize public …
with updated results poses significant resource challenges. We aimed to characterize public …