VIR-7831 and VIR-7832 are dual action monoclonal antibodies (mAbs) targeting the spike
glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). VIR-7831 …

Transmission-blocking strategies that slow the spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and protect against coronavirus disease 2019 (COVID-19) are …

Apical constriction changes cell shapes, driving critical morphogenetic events, including
gastrulation in diverse organisms and neural tube closure in vertebrates. Apical constriction is …

Background Necrotizing enterocolitis (NEC) develops through exaggerated toll-like receptor
4 (TLR4) signaling in the intestinal epithelium. Breast milk is rich in non-digestible …

Chromosome instability and aneuploidy are hallmarks of cancer, but it is not clear how changes
in the chromosomal content of a cell contribute to the malignant phenotype. Previously …

Angiotensin-converting enzyme 2 (ACE2) is a potent negative regulator capable of
restraining overactivation of the renin–angiotensin system, which contributes to exuberant …

Background & Aims Necrotizing enterocolitis (NEC) is a devastating disease of premature
infants characterized by Toll-like receptor 4 (TLR4)-dependent intestinal inflammation and …

Background Vaccines that are shelf stable and easy to administer are crucial to improve
vaccine access and reduce severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Short bowel syndrome is a major cause of morbidity and mortality in children. Despite decades
of experience in the management of short bowel syndrome, current therapy is primarily …

The redox status of the cysteine-rich SARS-CoV-2 spike glycoprotein (SARS-2-S) is important
for the binding of SARS-2-S to angiotensin-converting enzyme 2 (ACE2), suggesting that …