Drug use represents a significant burden to public health through disease, disability and
social problems, and policy makers are becoming increasingly interested in how to develop …

Opioid agonist therapy was introduced in Canada in 1959 with the use of methadone for the
treatment of opioid dependence. The regulation of methadone was the responsibility of …

Health care administrative data are generated at every encounter with the health care
system, whether through a visit to a physician's office, a diagnostic procedure, an admission …

Aims To characterize the impacts of policies intended to improve opioid prescribing and
prevent opioid-related overdose and death on individuals who take opioids. Methods We …

The Beers Criteria are a valuable tool for clinical care and quality improvement but may be
misinterpreted and implemented in ways that cause unintended harms. This article …

CMAJ, December 6, 2016, 188 (17–18) 1241 to remove it from their drug formularies. 13
Oxycodone prescribing decreased, but there was a shift to prescribing other potent opioids …

Background As several regulatory and environmental changes have occurred in North
America, trends in overdose deaths were examined in the United States (US), Ontario and …

In Canada, opioid-related overdose mortality has steeply increased in recent years; as a
substantial number of opioid-related deaths are related to fentanyl products, this …

Background: Levels of prescription opioid (PO) dispensing have been rising in Canada–also
in global comparison–since the mid-2000s, and are co-occurring with extensive PO-related …

Prescription drug monitoring programs (PDMPs) are a crucial component of federal and
state governments' response to the opioid epidemic. Evidence about the effectiveness of …