Drugs for insomnia beyond benzodiazepines: pharmacology, clinical applications, and discovery
Although the GABAergic benzodiazepines (BZDs) and Z-drugs (zolpidem, zopiclone, and
zaleplon) are FDA-approved for insomnia disorders with a strong evidence base, they have …
zaleplon) are FDA-approved for insomnia disorders with a strong evidence base, they have …
Deprescribing antipsychotics for behavioural and psychological symptoms of dementia and insomnia: evidence-based clinical practice guideline
LM Bjerre, B Farrell, M Hogel, L Graham… - Canadian Family …, 2018 - cfp.ca
Objective To develop an evidence-based guideline to help clinicians make decisions about
when and how to safely taper and stop antipsychotics; to focus on the highest level of …
when and how to safely taper and stop antipsychotics; to focus on the highest level of …
20-year trends in the pharmacologic treatment of bipolar disorder by psychiatrists in outpatient care settings
Objective: Pharmacological options for treating bipolar disorder have increased over the
past 20 years, with several second-generation antipsychotics receiving regulatory approval …
past 20 years, with several second-generation antipsychotics receiving regulatory approval …
Off-label prescribing of antipsychotics in adults, children and elderly individuals: a systematic review of recent prescription trends
L Carton, O Cottencin… - Current …, 2015 - ingentaconnect.com
Introduction: New antipsychotics continuously arrive on the market, which thereby influences
the approved and off-label prescribing (OLP) schemes. We aimed to identify the recent …
the approved and off-label prescribing (OLP) schemes. We aimed to identify the recent …
British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: an update
S Wilson, K Anderson, D Baldwin… - Journal of …, 2019 - journals.sagepub.com
This British Association for Psychopharmacology guideline replaces the original version
published in 2010, and contains updated information and recommendations. A consensus …
published in 2010, and contains updated information and recommendations. A consensus …
Metabolic adverse effects of off-label use of second-generation antipsychotics in the adult population: a systematic review and meta-analysis
N Stogios, E Smith, S Bowden, V Tran… - …, 2022 - nature.com
Prescription rates of second-generation antipsychotics (SGAs) are rapidly increasing for non-
indicated (ie, off-label) usage. SGAs used for approved indications are associated with …
indicated (ie, off-label) usage. SGAs used for approved indications are associated with …
Deprescribing benzodiazepines and Z-drugs in community-dwelling adults: a scoping review
AS Pollmann, AL Murphy, JC Bergman… - BMC pharmacology and …, 2015 - Springer
Background Long-term sedative use is prevalent and associated with significant morbidity,
including adverse events such as falls, cognitive impairment, and sedation. The …
including adverse events such as falls, cognitive impairment, and sedation. The …
Controversies regarding lithium-associated weight gain: case–control study of real-world drug safety data
W Greil, M de Bardeci, B Müller-Oerlinghausen… - International journal of …, 2023 - Springer
Background The impact of long-term lithium treatment on weight gain has been a
controversial topic with conflicting evidence. We aim to assess reporting of weight gain …
controversial topic with conflicting evidence. We aim to assess reporting of weight gain …
Atypical antipsychotics for insomnia: a systematic review
Background Observational evidence suggests that atypical antipsychotics such as
quetiapine are increasingly being used to manage insomnia. This is concerning given the …
quetiapine are increasingly being used to manage insomnia. This is concerning given the …
Comparative effectiveness and safety of antipsychotic drugs in schizophrenia treatment: a real‐world observational study
A Vanasse, L Blais, J Courteau… - Acta Psychiatrica …, 2016 - Wiley Online Library
Objective The objective was to compare, in a real‐world setting, the risk of mental and
physical health events associated with different antipsychotic drugs (clozapine, olanzapine …
physical health events associated with different antipsychotic drugs (clozapine, olanzapine …