User profiles for Stephen Mac

Stephen Mac

University of Toronto
Verified email at mail.utoronto.ca
Cited by 559

The economic burden of Lyme disease and the cost-effectiveness of Lyme disease interventions: A scoping review

S Mac, SR da Silva, B Sander - PLoS One, 2019 - journals.plos.org
Introduction While Lyme disease (LD) is mostly treatable, misdiagnosed or untreated LD can
result in debilitating sequelae and excessive healthcare usage. The objective of this review …

Cost-effectiveness of palivizumab for respiratory syncytial virus: a systematic review

S Mac, A Sumner, S Duchesne-Belanger, R Stirling… - …, 2019 - publications.aap.org
OBJECTIVE: To systematically review the cost-effectiveness of palivizumab prophylaxis
compared with no prophylaxis in infants< 24 months of age. DATA SOURCES: Medline, Embase…

Chromosome-scale, haplotype-resolved assembly of human genomes

…, A Carroll, M Chou, A Schmitt, X Zhou, S Mac… - Nature …, 2021 - nature.com
Haplotype-resolved or phased genome assembly provides a complete picture of genomes
and their complex genetic variations. However, current algorithms for phased assembly either …

Estimation of COVID-19–induced depletion of hospital resources in Ontario, Canada

K Barrett, YA Khan, S Mac, R Ximenes, DMJ Naimark… - Cmaj, 2020 - Can Med Assoc
BACKGROUND: The global spread of coronavirus disease 2019 (COVID-19) continues in
several jurisdictions, causing substantial strain to health care systems. The purpose of our …

Long-term sequelae and health-related quality of life associated with Lyme disease: a systematic review

S Mac, S Bahia, F Simbulan… - Clinical Infectious …, 2020 - academic.oup.com
Lyme disease (LD) is the most commonly reported vector-borne disease, but its clinical
consequences remain uncertain. We conducted a systematic review of the long-term sequelae …

Simulation-based estimation of SARS-CoV-2 infections associated with school closures and community-based nonpharmaceutical interventions in Ontario, Canada

…, S Mishra, K Barrett, YA Khan, S Mac… - JAMA Network …, 2021 - jamanetwork.com
Importance Resurgent COVID-19 cases have resulted in the reinstitution of nonpharmaceutical
interventions, including school closures, which can have adverse effects on families. …

Burden of illness associated with Respiratory Syncytial Virus (RSV)-related hospitalizations among adults in Ontario, Canada: A retrospective population-based study

S Mac, S Shi, B Millson, A Tehrani, M Eberg, V Myageri… - Vaccine, 2023 - Elsevier
Background Globally, RSV is a common viral pathogen that causes 64 million acute
respiratory infections annually. Our objective was to determine the incidence of hospitalization, …

Does biomarker use in oncology improve clinical trial failure risk? A large‐scale analysis

JL Parker, SS Kuzulugil, K Pereverzev, S Mac… - Cancer …, 2021 - Wiley Online Library
Purpose To date there has not been an extensive analysis of the outcomes of biomarker use
in oncology. Methods Data were pooled across four indications in oncology drawing upon …

[HTML][HTML] Benchmarking ultra-high molecular weight DNA preservation methods for long-read and long-range sequencing

…, K Oliver, M Smith, W Tan, A Kraus, S Mac… - …, 2022 - academic.oup.com
Background Studies in vertebrate genomics require sampling from a broad range of tissue
types, taxa, and localities. Recent advancements in long-read and long-range genome …

Efficient chromosome-scale haplotype-resolved assembly of human genomes

…, A Carroll, M Chou, A Schmitt, X Zhou, S Mac… - BioRxiv, 2019 - biorxiv.org
Haplotype-resolved or phased sequence assembly provides a complete picture of genomes
and complex genetic variations. However, current phased assembly algorithms either fail to …