[BOOK][B] Bayesian adaptive methods for clinical trials
Already popular in the analysis of medical device trials, adaptive Bayesian designs are
increasingly being used in drug development for a wide variety of diseases and conditions, from …
increasingly being used in drug development for a wide variety of diseases and conditions, from …
Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial
…, MR Reynolds, C Vinekar, CY Liu, SM Berry, DA Berry… - Jama, 2010 - jamanetwork.com
Context Antiarrhythmic drugs are commonly used for prevention of recurrent atrial fibrillation
(AF) despite inconsistent efficacy and frequent adverse effects. Catheter ablation has been …
(AF) despite inconsistent efficacy and frequent adverse effects. Catheter ablation has been …
Effect of hydrocortisone on mortality and organ support in patients with severe COVID-19: the REMAP-CAP COVID-19 corticosteroid domain randomized clinical trial
Importance Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19)
is limited. Objective To determine whether hydrocortisone improves outcome for …
is limited. Objective To determine whether hydrocortisone improves outcome for …
Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis
Importance Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized
for COVID-19 have variously reported benefit, no effect, and harm. Objective To estimate the …
for COVID-19 have variously reported benefit, no effect, and harm. Objective To estimate the …
A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease
Dominantly inherited Alzheimer’s disease (DIAD) causes predictable biological changes
decades before the onset of clinical symptoms, enabling testing of interventions in the …
decades before the onset of clinical symptoms, enabling testing of interventions in the …
[HTML][HTML] Cetuximab for the treatment of colorectal cancer
…, JR Zalcberg, D Tu, HJ Au, SR Berry… - … England Journal of …, 2007 - Mass Medical Soc
Background Cetuximab, an IgG1 chimeric monoclonal antibody against epidermal growth
factor receptor (EGFR), has activity against colorectal cancers that express EGFR. Methods …
factor receptor (EGFR), has activity against colorectal cancers that express EGFR. Methods …
Interleukin-6 receptor antagonists in critically ill patients with Covid-19–preliminary report
Background The efficacy of interleukin-6 receptor antagonists in critically ill patients with
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
coronavirus disease 2019 (Covid-19) is unclear. Methods We evaluated tocilizumab and …
[HTML][HTML] A minimal common outcome measure set for COVID-19 clinical research
Clinical research is necessary for an effective response to an emerging infectious disease
outbreak. However, research efforts are often hastily organised and done using various …
outbreak. However, research efforts are often hastily organised and done using various …
Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial
…, M Kraft, NS Shargill, J Quiring, SM Berry… - American journal of …, 2010 - atsjournals.org
Rationale: Bronchial thermoplasty (BT) is a bronchoscopic procedure in which controlled
thermal energy is applied to the airway wall to decrease smooth muscle. Objectives: To …
thermal energy is applied to the airway wall to decrease smooth muscle. Objectives: To …
Bayesian smoothing and regression splines for measurement error problems
SM Berry, RJ Carroll, D Ruppert - Journal of the American …, 2002 - Taylor & Francis
In the presence of covariate measurement error, estimating a regression function nonparametrically
is extremely difficult, the problem being related to deconvolution. Various frequentist …
is extremely difficult, the problem being related to deconvolution. Various frequentist …