In vitro microvessels for the study of angiogenesis and thrombosis

Y Zheng, J Chen, M Craven, NW Choi… - Proceedings of the …, 2012 - National Acad Sciences
Microvascular networks support metabolic activity and define microenvironmental conditions
within tissues in health and pathology. Recapitulation of functional microvascular structures …

Microfluidic scaffolds for tissue engineering

NW Choi, M Cabodi, B Held, JP Gleghorn… - Nature materials, 2007 - nature.com
Most methods to culture cells in three dimensions depend on a cell-seedable biomaterial to
define the global structure of the culture and the microenvironment of the cells. Efforts to …

Radiation dose and second cancer risk in patients treated for cancer of the cervix

…, P Fraser, FE Neal, P Prior, NW Choi… - Radiation …, 1988 - meridian.allenpress.com
The risk of cancer associated with a broad range of organ doses was estimated in an
international study of women with cervical cancer. Among 150,000 patients reported to one of 19 …

Second cancers following radiation treatment for cervical cancer. An international collaboration among cancer registries

…, LA Brinton, R Brown, NW Choi… - Journal of the …, 1985 - academic.oup.com
The numbers of second cancers among 182,040 women treated for cervical cancer that
were reported to 15 cancer registries in 8 countries were compared to the numbers expected …

Non-Hodgkin's lymphoma and specific pesticide exposures in men: cross-Canada study of pesticides and health

…, JA Dosman, D Robson, LF Skinnider, NW Choi - … Biomarkers & Prevention, 2001 - AACR
Our objective in the study was to investigate the putative associations of specific pesticides
with non-Hodgkin’s Lymphoma [NHL; International Classification of Diseases, version 9 (ICD-…

Dense type I collagen matrices that support cellular remodeling and microfabrication for studies of tumor angiogenesis and vasculogenesis in vitro

VL Cross, Y Zheng, NW Choi, SS Verbridge… - Biomaterials, 2010 - Elsevier
… For example, Choi et al. fabricated microfluidic networks within mechanically robust
calcium alginate hydrogels to deliver signaling factors to cells embedded within the bulk of the …

Dietary factors and the incidence of cancer of the stomach

HA RISCH, M JAIN, NW Choi… - American journal of …, 1985 - academic.oup.com
A case-control study of diet and stomach cancer was conducted during 1979–1982 in Toronto,
Winnipeg, and St John's, Canada. Two hundred forty-six histologically verified cancer …

A microfluidic biomaterial

M Cabodi, NW Choi, JP Gleghorn… - Journal of the …, 2005 - ACS Publications
We report on the incorporation of microfluidic structure within a high-water-content hydrogel [4%
(w/v) calcium alginate]. We used the microfluidic network to control the chemical …

Radiation dose and leukemia risk in patients treated for cancer of the cervix.

…, P Fraser, M Palmer, P Prior, NW Choi… - Journal of the …, 1987 - europepmc.org
To quantify the risk of radiation-induced leukemia and provide further information on the
nature of the relationship between dose and response, a case-control study was undertaken in …

Formation of microvascular networks in vitro

…, Y Zheng, SS Verbridge, J Chen, M Craven, NW Choi… - Nature protocols, 2013 - nature.com
This protocol describes how to form a 3D cell culture with explicit, endothelialized microvessels.
The approach leads to fully enclosed, perfusable vessels in a bioremodelable hydrogel (…