Electronic cigarettes (e-cigarettes or e-cigs) are designed to heat and aerosolize mixtures of
vegetable glycerin, propylene glycol, nicotine, and flavoring additives, thus delivering …

The molecular circadian clock is a self-regulating transcription/translation cycle of positive (Bmal1,
Clock/Npas2) and negative (Per1,2,3, Cry1,2) regulatory components. While the …

Glucocorticoid hormones are a powerful mammalian systemic hormonal signal that exerts
regulatory effects on almost every cell and system of the body. Glucocorticoids act in a …

On 25 January 2018, the Food and Drug Administration (FDA) Tobacco Scientific Advisory
Committee unanimously voted (with one abstention) that Phillip Morris International (PMI) …

Introduction Heated tobacco products are being touted as novel reduced-harm tobacco
products by tobacco companies. In the USA, Philip Morris International submitted a modified risk …

Importance The COVID-19 pandemic has impacted cancer systems worldwide. Quantifying
the changes is critical to informing the delivery of care while the pandemic continues, as well …

Mood disorders are associated with dysregulation of prefrontal cortex (PFC) function, circadian
rhythms, and diurnal glucocorticoid (corticosterone [CORT]) circulation. Entrainment of …

The degree of behavioural control that an organism has over a stressor is a potent modulator
of the stressor's impact; controllable stressors produce none of the neurochemical and …

Oscillating clock gene expression gives rise to a molecular clock that is present not only in
the body’s master circadian pacemaker, the hypothalamic suprachiasmatic nucleus (SCN), …

Actual or perceived behavioral control during a traumatic event can promote resilience
against future adversity, but the long-term cellular and circuit mechanisms by which this …