Current use of routinely collected health data to complement randomized controlled trials: a meta-epidemiological survey
LG Hemkens, DG Contopoulos-Ioannidis… - … Open Access Journal, 2016 - cmajopen.ca
Background: Studies that use routinely collected health data (RCD studies) are advocated to
complement evidence from randomized controlled trials (RCTs) for comparative …
complement evidence from randomized controlled trials (RCTs) for comparative …
Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey
LG Hemkens, DG Contopoulos-Ioannidis… - bmj, 2016 - bmj.com
Objective To assess differences in estimated treatment effects for mortality between
observational studies with routinely collected health data (RCD; that are published before …
observational studies with routinely collected health data (RCD; that are published before …
[HTML][HTML] Routinely collected data for randomized trials: promises, barriers, and implications
Background Routinely collected health data (RCD) are increasingly used for randomized
controlled trials (RCTs). This can provide three major benefits: increasing value through …
controlled trials (RCTs). This can provide three major benefits: increasing value through …
[HTML][HTML] Generalizability of findings from randomized controlled trials is limited in the leading general medical journals
A Malmivaara - Journal of clinical epidemiology, 2019 - Elsevier
Objectives To document reporting of study characteristics of randomized controlled trials
(RCTs) in the four leading general medical journals and to appraise the generalizability of …
(RCTs) in the four leading general medical journals and to appraise the generalizability of …
No differences were found between effect estimates from conventional and registry-based randomized controlled trials
T Mathes, P Klaßen, D Pieper - Journal of Clinical Epidemiology, 2019 - Elsevier
Objectives The study aims to assess whether the results from registry-based randomized
controlled trials (RRCTs) systematically differ from the results of conventional randomized …
controlled trials (RRCTs) systematically differ from the results of conventional randomized …
Treatment effects in randomised trials using routinely collected data for outcome assessment versus traditional trials: meta-research study
Objective To compare effect estimates of randomised clinical trials that use routinely
collected data (RCD-RCT) for outcome ascertainment with traditional trials not using …
collected data (RCD-RCT) for outcome ascertainment with traditional trials not using …
Why all randomised controlled trials produce biased results
A Krauss - Annals of medicine, 2018 - Taylor & Francis
Abstract Background: Randomised controlled trials (RCTs) are commonly viewed as the
best research method to inform public health and social policy. Usually they are thought of …
best research method to inform public health and social policy. Usually they are thought of …
[HTML][HTML] The reporting of studies using routinely collected health data was often insufficient
Objectives To assess reporting quality of studies using routinely collected health data (RCD)
to inform the REporting of studies Conducted using Observational Routinely collected health …
to inform the REporting of studies Conducted using Observational Routinely collected health …
Registry-based randomized controlled trials merged the strength of randomized controlled trails and observational studies and give rise to more pragmatic trials
T Mathes, S Buehn, P Prengel, D Pieper - Journal of clinical epidemiology, 2018 - Elsevier
Objectives The objective of this study was to analyze the features of registry-based
randomized trials (rRCTs). Study Design and Setting We systematically searched PubMed …
randomized trials (rRCTs). Study Design and Setting We systematically searched PubMed …
The RECORD reporting guidelines: meeting the methodological and ethical demands of transparency in research using routinely-collected health data
SG Nicholls, SM Langan, HT Sørensen… - Clinical …, 2016 - Taylor & Francis
Routinely-collected health data (RCD) are now used for a wide range of studies, including
observational studies, comparative effectiveness research, diagnostics, studies of adverse …
observational studies, comparative effectiveness research, diagnostics, studies of adverse …
