Excess burden of age-associated comorbidities among people living with HIV in British Columbia, Canada: a population-based cohort study

NGA Nanditha, A Paiero, HM Tafessu, M St-Jean… - BMJ open, 2021 - bmjopen.bmj.com
Objectives As people living with HIV (PLWH) live longer, morbidity and mortality from non-AIDS
comorbidities have emerged as major concerns. Our objective was to compare …

Rapid Initiation of Injection Naltrexone for Opioid Use Disorder: A Stepped-Wedge Cluster Randomized Clinical Trial

M Shulman, MG Greiner, HM Tafessu… - JAMA Network …, 2024 - jamanetwork.com
Importance Injectable extended-release (XR)-naltrexone is an effective treatment option for
opioid use disorder (OUD), but the need to withdraw patients from opioid treatment prior to …

A province-wide HIV initiative to accelerate initiation of treatment-as-prevention and virologic suppression in British Columbia, Canada: a population-based cohort …

…, X Dong, HM Tafessu, L Wang, M Lu… - … Open Access Journal, 2022 - cmajopen.ca
Background: In 2010, HIV treatment as prevention (TasP), encompassing widespread HIV
testing and immediate initiation of free antiretroviral treatment (ART), was piloted under the …

The uptake of family screening in hypertrophic cardiomyopathy and an online video intervention to facilitate family communication

…, AL Cirino, CW Carr, HM Tafessu… - … Genetics & Genomic …, 2019 - Wiley Online Library
Background Individuals with hypertrophic cardiomyopathy (HCM), even when asymptomatic,
are at‐risk for sudden cardiac death and stroke from arrhythmias, making it imperative to …

Disparities in multimorbidity and mortality among people living with and without HIV across British Columbia's health regions: a population-based cohort study

NGA Nanditha, G Zheng, HM Tafessu… - Canadian Journal of …, 2021 - Springer
Objectives Longer survival has increased the likelihood of antiretroviral-treated people living
with HIV (PLWH) developing age-associated comorbidities. We compared the burden of …

Healthcare utilisation and costs associated with adherence to antipsychotics among people living with HIV/AIDS and schizophrenia: a population-based cohort study …

…, NGA Nanditha, HM Tafessu, H Nathani, M St-Jean… - BMJ open, 2023 - bmjopen.bmj.com
Objectives Non-adherence to antipsychotics is the greatest obstacle to treating schizophrenia.
We assessed the economic and clinical impacts of adherence to antipsychotics among …

Surmounting withdrawal to initiate fast treatment with naltrexone (SWIFT): A stepped wedge hybrid type 1 effectiveness-implementation study

…, O Opara, K Potter, DC Voronca, HM Tafessu… - Contemporary clinical …, 2023 - Elsevier
Background Extended-release injectable naltrexone (XR-NTX) is an effective treatment for
opioid use disorder (OUD), but initiation remains a barrier to implementation. Standard …

[HTML][HTML] Missed opportunities for earlier diagnosis of HIV in British Columbia, Canada: A retrospective cohort study

…, M St-Jean, H Tafessu, SA Guillemi, MW Hull, M Lu… - PLoS …, 2019 - journals.plos.org
Background Late HIV diagnosis is associated with increased AIDS-related morbidity and
mortality as well as an increased risk of HIV transmission. In this study, we quantified and …

The syndemic effect of HIV/HCV co-infection and mental health disorders on acute care hospitalization rate among people living with HIV/AIDS: a population-based …

M St-Jean, H Tafessu, K Closson, TL Patterson… - Canadian Journal of …, 2019 - Springer
Objective Our primary objective was to examine the syndemic effect of HIV/HCV co-infection
and mental health disorders (MHD) on the acute care hospitalization rate among people …

Overdose mortality is reducing the gains in life expectancy of antiretroviral-treated people living with HIV in British Columbia, Canada

M St-Jean, X Dong, H Tafessu, D Moore… - International Journal of …, 2021 - Elsevier
Background A remarkable reduction in AIDS-related mortality has been achieved through the
widespread use of triple combination antiretroviral therapy, considerably increasing the life …