Temperature-induced unfolding of three humanized IgG1 monoclonal antibodies and their
Fab and Fc fragments was monitored by differential scanning calorimetry at neutral pH. With …

We expand the understanding of hinge-region degradation of human IgG1 monoclonal
antibodies. First, our data more accurately confirm previously proposed hydrolysis of the CO−NH …

Conventional influenza vaccines can prevent infection, but their efficacy depends on the
degree of antigenic “match” between the strains used for vaccine preparation and those …

Congenital infection of human cytomegalovirus (HCMV) is one of the leading causes of
nongenetic birth defects, and development of a prophylactic vaccine against HCMV is of high …

The development of fermentation processes for recombinant vaccines requires optimizing
expression while maintaining high product quality. Changes to cell fermentation conditions …

Chronic pain is common among people with human immunodeficiency virus (HIV) and
detrimental to quality of life and overall health. It is often underdiagnosed, undertreated, and …

Background Social determinants of health (SDOH) may influence the probability of people
living with HIV also being infected with hepatitis C virus (HCV). We compared the SDOH of …

Background: With combination antiretroviral therapy (ART) and increased longevity, cancer
is a leading cause of morbidity among people with HIV. We characterized trends in cancer …

Introduction Our aim is to evaluate the implementation of an online telecoaching community-based
exercise (CBE) intervention with the goal of reducing disability and enhancing …

Clostridium difficile strains producing binary toxin, in addition to toxin A (TcdA) and toxin B (TcdB),
have been associated with more severe disease and increased recurrence of C. …