Objectives To quantify and compare potential benefits (subjective reports of sleep variables)
and risks (adverse events and morning-after psychomotor impairment) of short term …

The resurgence of interest in anhedonia within major depression has been fuelled by
clinical trials demonstrating its utility in predicting antidepressant response as well as recent …

Buprenorphine is a semi-synthetic opioid derived from thebaine, a naturally occurring alkaloid
of the opium poppy, Papaver somniferum. The pharmacology of buprenorphine is unique …

Fuzzy pharmacology is a term coined to represent the application of fuzzy logic and fuzzy set
theory to pharmacological problems. Fuzzy logic is the science of reasoning, thinking and …

To characterize prescription opioid dependent patients in a methadone maintenance treatment
(MMT) program, a detailed retrospective chart review of new admissions (1997–1999, n=…

Consumers of psychiatric medications or services may be stigmatized by health care providers.
The authors surveyed community pharmacists (N=283) in the greater Toronto area to …

Anhedonia, a core symptom of Major Depressive Disorder (MDD), is predictive of
antidepressant non-response. In contrast to the definition of anhedonia as a “loss of pleasure”, …

The potential for drug-drug interactions in psychiatric patients is very high as combination
psychopharmacotherapy is used to treat comorbid psychiatric disorders, to treat the adverse …

The pharmacotherapeutic use of lithium in the elderly as acute and maintenance therapy in
bipolar disorder and augmentation therapy for major depression is well documented. …

The purposes of this study were to examine predictors of benzodiazepine use among
methadone maintenance treatment patients, to determine whether baseline benzodiazepine use …