Abstract
Observational methods are evolving in response to the widespread availability of data from clinical registries, electronic health records, and administrative databases. These approaches will never eliminate the need for randomized trials, but clearly have a role in evaluating the effect of therapies in unselected populations treated in routine practice.
Copyright © 2013 Elsevier Inc. All rights reserved.
MeSH terms
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Comparative Effectiveness Research* / methods
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Comparative Effectiveness Research* / statistics & numerical data
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Data Interpretation, Statistical
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Databases, Factual / statistics & numerical data
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Electronic Health Records / statistics & numerical data
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Heart Failure* / diagnosis
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Heart Failure* / epidemiology
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Heart Failure* / therapy
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Humans
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Observation / methods*
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Outcome and Process Assessment, Health Care / statistics & numerical data*
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Randomized Controlled Trials as Topic* / methods
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Randomized Controlled Trials as Topic* / statistics & numerical data
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Registries / statistics & numerical data
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Research Design*