Hepatocellular carcinoma: epidemiology, surveillance, and diagnosis

Semin Liver Dis. 2010 Feb;30(1):3-16. doi: 10.1055/s-0030-1247128. Epub 2010 Feb 19.

Abstract

Hepatocellular carcinoma (HCC) is increasing in incidence in many countries, and is the most common cause of death in patients with cirrhosis. With regular surveillance, small early HCC lesions can be identified. An algorithm has been developed that allows for diagnosis of these lesions. Very early HCC lesions have high cure rates with appropriate treatment. If all these factors are in place most HCCs can be cured.

Publication types

  • Review

MeSH terms

  • Carcinoma, Hepatocellular / diagnosis*
  • Carcinoma, Hepatocellular / epidemiology*
  • Carcinoma, Hepatocellular / therapy
  • Carcinoma, Hepatocellular / virology
  • Combined Modality Therapy
  • Early Detection of Cancer
  • Female
  • Hepatitis B, Chronic / pathology
  • Hepatitis C, Chronic / pathology
  • Humans
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / epidemiology*
  • Liver Neoplasms / therapy
  • Liver Neoplasms / virology
  • Male
  • Observation
  • Precancerous Conditions / pathology*
  • Prognosis
  • Risk Assessment
  • Survival Analysis