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African American ESRD patients have a high pre-dialysis prevalence of kidney stones compared to NHANES III

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Abstract

If nephrolithiasis (NL) promotes progression to end stage renal disease (ESRD), requiring renal replacement therapy, one might expect a higher prevalence of pre-ESRD stones among ESRD versus non-ESRD subjects. We compared the prevalence of pre-ESRD stones in an African-American (AA) hemodialysis (HD) population to the estimated stone prevalence in a nationally representative cohort of AA persons as obtained by the Third National Health and Nutrition Survey (NHANES III). Face-to-face questionnaires were administered to a sample of 300 AA HD patients undergoing dialysis therapy at the University of Chicago to determine pre-ESRD NL prevalence. All data on pre-ESRD stone prevalence was confirmed by documented medical history, radiology and laboratory findings, where available. Prevalence of pre-ESRD NL in AA HD patients was 8.3% versus 2.8% in the age, race and sex adjusted NHANES III population (P < 0.001). After adjustment for age and sex, it was estimated that the prevalence of pre-ESRD kidney stones among AA HD patients is significantly higher than the prevalence of kidney stones found in the general AA population.

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Authors and Affiliations

  1. Department of Medicine, University of Chicago, 5841 South Maryland Ave. MC 5100, Chicago, IL, 60637, USA

    Nicole Stankus, Mary Hammes & Elaine Worcester

  2. Division of Epidemiology, University of California, 224 Irvine Hall, Irvine, CA, 92697, USA

    Daniel Gillen

Authors
  1. Nicole Stankus
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  2. Mary Hammes
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  3. Daniel Gillen
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  4. Elaine Worcester
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Correspondence to Nicole Stankus.

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Stankus, N., Hammes, M., Gillen, D. et al. African American ESRD patients have a high pre-dialysis prevalence of kidney stones compared to NHANES III. Urol Res 35, 83–87 (2007). https://doi.org/10.1007/s00240-007-0079-3

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  • DOI: https://doi.org/10.1007/s00240-007-0079-3

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