Table 1:

Evaluation of therapeutic value

OrganizationNew therapeutic valueWebsite for definition of therapeutic value
MajorModerateLittle to no additional therapeutic value
Human Drug Advisory Panel (Patented Medicine Prices Review Board)Breakthrough, substantial improvementModerate improvement — primary and moderate improvement — secondarySlight or no improvementhttp://www.pmprb-cepmb.gc.ca/view.asp?ccid = 492#1635
Prescrire InternationalBravo, a real advanceOffers an advantagePossibly helpful, nothing new, not acceptablehttp://english.prescrire.org/en/81/168/46800/0/NewsDetails.aspx