Table 1:

Evaluation of therapeutic value

OrganizationNew therapeutic valueWebsite for definition of therapeutic value
MajorModerateLittle to no additional therapeutic value
Human Drug Advisory Panel (Patented Medicine Prices Review Board)Breakthrough, substantial improvementModerate improvement — primary and moderate improvement — secondarySlight or no improvement = 492#1635
Prescrire InternationalBravo, a real advanceOffers an advantagePossibly helpful, nothing new, not acceptable