Crude outcomes at 1 year
| Outcome | Year | p value* | |||||||
|---|---|---|---|---|---|---|---|---|---|
| 2008/09 | 2009/10 | 2010/11 | 2011/12 | 2012/13 | 2013/14 | 2014/15 | 2015/16 | ||
| Overall cohort | n = 7070 | n = 8128 | n = 8763 | n = 8690 | n = 7203 | n = 7353 | n = 8315 | n = 8571 | |
| Ischemic stroke | 310 (4.4) | 298 (3.7) | 280 (3.2) | 302 (3.5) | 232 (3.2) | 234 (3.2) | 263 (3.2) | 268 (3.1) | 0.01 |
| Major bleeding | 359 (5.1) | 341 (4.2) | 379 (4.3) | 395 (4.5) | 351 (4.9) | 341 (4.6) | 408 (4.9) | 422 (4.9) | 0.3 |
| High stroke risk | n = 4084 | n = 4401 | n = 4838 | n = 5184 | n = 4087 | n = 4217 | n = 4676 | n = 4712 | |
| Initiation of oral anticoagulant therapy within 1 yr | 2095 (51.3) | 2258 (51.3) | 2483 (51.3) | 2944 (56.8) | 2420 (59.2) | 2217 (52.6) | 2678 (57.3) | 3085 (65.5) | 0.02 |
| Persistence with oral anticoagulant therapy | 1283 (31.4) | 1355 (30.8) | 1500 (31.0) | 1920 (37.0) | 1607 (39.3) | 1373 (32.6) | 1472 (31.5) | 1976 (41.9) | 0.1 |
| Moderate stroke risk | n = 1519 | n = 1697 | n = 1960 | n = 1797 | n = 1675 | n = 1655 | n = 2033 | n = 2075 | |
| Initiation of oral anticoagulant therapy within 1 yr | 680 (44.8) | 670 (39.5) | 769 (39.2) | 899 (50.0) | 828 (49.4) | 676 (40.8) | 855 (42.1) | 1071 (51.6) | 0.4 |
| Persistence with oral anticoagulant therapy | 380 (25.0) | 356 (21.0) | 422 (21.5) | 538 (29.9) | 488 (29.1) | 375 (22.7) | 392 (19.3) | 595 (28.7) | 0.9 |
↵* Mann–Kendall test for monotonic trends.