Table 6:

Multivariable model of dexamethasone as the main predictor of delirium incidence in adults aged ≥ 65 years admitted to acute care hospitals with COVID-19 in wave 2 of the COVID-19 pandemic*

VariableUnadjusted ORAdjusted OR
Dexamethasone use2.11 (1.32–3.46)1.38 (0.77–2.50)
Remdesivir use0.93 (0.53–1.58)1.56 (0.80–3.04)
Tocilizumab use2.19 (0.74–6.53)2.53 (0.73–9.24)
Age, yr1.31 (1.17–1.48)1.21 (1.04–1.40)
Dementia4.99 (2.86–8.89)3.25 (1.67–6.45)
Clinical Frailty Scale score1.53 (1.32–1.79)1.53 (1.24–1.91)
Intensive care unit admission2.94 (1.82–4.77)6.82 (3.65–13.11)
  • Note: OR = odds ratio.

  • * Number of records in model: 395; Hosmer–Lemeshow test: p = 0.57; C statistic: 0.800.

  • Adjusted for remdesivir use, tocilizumab use, age, dementia, Clinical Frailty Scale and intensive care unit admission.

  • Each 5-year increase.