Table 3:

Outcome associations during wave 3, stratified by variant of concern and vaccination status^*

Variable	All-cause hospitalization, aOR (95% CI)			Death, aOR (95% CI)

	Alberta	Ontario	Pooled	Alberta	Ontario	Pooled
Variant of concern

Wild-type	Reference

Alpha variant	1.86 (1.73–2.00)	1.48 (1.41–1.56)	1.59 (1.53–1.66)	1.64 (1.32–2.04)	1.19 (1.05–1.35)	1.29 (1.16–1.44)

Delta variant	2.7 (1.91–3.81)	1.76 (1.52–2.04)	1.88 (1.64–2.15)	4.97 (2.37–10.43)	1.67 (1.17–2.38)	2.05 (1.49–2.82)

Vaccination status

Unvaccinated	Reference

Partially vaccinated	0.44 (0.38–0.51)	0.42 (0.39–0.44)	0.42 (0.40–0.45)	0.61 (0.46–0.81)	0.40 (0.35–0.46)	0.43 (0.38–0.49)

Fully vaccinated	0.55 (0.36–0.83)	0.18 (0.15–0.22)	0.22 (0.18–0.26)	0.98 (0.55–1.77)	0.33 (0.25–0.45)	0.41 (0.32–0.53)