Baseline characteristics of patients with hospital-acquired and non-hospital-acquired SARS-CoV-2 infection
| Characteristic | No. (%)* of hospital-acquired cases n = 253 (36.3%) | No. (%)* of non-hospital-acquired cases n = 444 (63.7%) | p value |
|---|---|---|---|
| Age, yr, median (IQR) | 79 (68–86) | 73 (58.5–85) | |
| Age, yr | 0.003 | ||
| < 75 | 98 (38.7) | 231 (52.0) | |
| 75–84 | 71 (28.1) | 100 (22.5) | |
| ≥ 85 | 84 (33.2) | 113 (25.5) | |
| Female sex | 128 (50.6) | 228 (51.4) | 0.85 |
| Comorbidity† | |||
| Moderate to severe chronic kidney disease‡ | 35 (13.8) | 52 (11.7) | 0.42 |
| Solid tumour | < 0.001 | ||
| Localized | 49 (19.4) | 39 (8.8) | |
| Metastatic | 28 (11.1) | 14 (3.2) | |
| Hematologic malignancy | 12 (4.7) | 10 (2.3) | 0.07 |
| Diabetes | 87 (34.4) | 156 (35.1) | 0.84 |
| COPD | 60 (23.7) | 65 (14.6) | 0.003 |
| Myocardial infarction | 18 (7.1) | 33 (7.4) | 0.91 |
| Dementia | 58 (22.9) | 101 (22.8) | 0.96 |
| Charlson Comorbidity Index, median (IQR) | 2 (1–4) | 1 (0–3) | |
| Provenance before admission§ | < 0.001 | ||
| Home | 180 (71.2) | 237 (53.4) | |
| Long-term care facility | 9 (3.6) | 49 (11.0) | |
| Others | 62 (24.4) | 160 (36.1) | |
| Reason for admission | < 0.001 | ||
| Infectious | 70 (27.9) | 7 (1.6) | |
| Nervous system | 38 (15.1) | 7 (1.6) | |
| Neoplasm | 37 (14.7) | 4 (0.9) | |
| Gastrointestinal | 21 (8.4) | 9 (2.0) | |
| Other | 85 (33.9) | 419 (93.9) | |
| Deprivation index of 4 or 5¶ | 150 (59.3) | 243 (54.7) | 0.16 |
| Timing of diagnosis, d | < 0.001 | ||
| 0–6 | 62 (24.5) | 444 (100) | |
| 7–14 | 91 (36.0) | 0 (0) | |
| > 14 | 100 (39.5) | 0 (0) | |
| Treatment with corticosteroids | 46 (18.2) | 66 (14.9) | 0.25 |
| Surgical procedure | 37 (14.6) | 13 (2.9) | 0.001 |
| ICU admission | 21 (8.3) | 85 (19.1) | < 0.001 |
| ICU admission within 7 days | 17 (81.0) | 74 (87.1) | 0.47 |
| Mechanical ventilation | 9 (3.6) | 58 (13.0) | 0.001 |
Note: COPD = chronic obstructive pulmonary disease, ICU = intensive care unit, IQR = interquartile range, RPA = Résidence privée pour ainés (private residences for older adults).
↵* Unless stated otherwise.
↵† Selected comorbidities from the Charlson Comorbidity Index.12
↵‡ Moderate to severe chronic renal disease, defined as creatinine > 265 μmol/L, as defined in the Charlson Comorbidity Index.12
↵§ Others: congregate living settings such as RPA, intermediate and family-type resources (IR-FTR), transfer from another hospital and rehabilitation.
↵¶ The deprivation index is based on patient postal code and 2016 census data. Results of various indicators are aggregated to create a deprivation index to identify a deprived population. A score from 1 (least deprived) to 5 (most deprived) is calculated, with 4 and 5 signifying being deprived and most deprived.11