Median time to vaccination for each of the routine childhood vaccinations in the pre-COVID-19 (Jan. 1, 2018, to Mar. 16, 2020) and COVID-19 (Mar. 17 to Nov. 30, 2020) periods
| Age and vaccination | Pre-COVID-19 | COVID-19 | p value* | ||||
|---|---|---|---|---|---|---|---|
| No. of eligible patients | No. of vaccinations | Median (95% CI) time to vaccination, mo | No. of eligible patients | No. of vaccinations | Median (95% CI) time to vaccination, mo | ||
| 2 mo, DTaP-IPV-Hib | 375 | 369 | 2.07 (2.07–2.10) | 131 | 130 | 2.10 (2.07–2.14) | 0.9453 |
| 2 mo, Pneu-C-13 | 375 | 365 | 2.07 (2.07–2.10) | 131 | 130 | 2.10 (2.07–2.14) | 0.9452 |
| 4 mo, DTaP-IPV-Hib | 330 | 328 | 4.14 (4.14–4.18) | 116 | 115 | 4.14 (4.11–4.21) | 0.4203 |
| 4 mo, Pneu-C-13 | 328 | 327 | 4.14 (4.14–4.18) | 115 | 113 | 4.14 (4.11–4.21) | 0.4794 |
| 6 mo, DTaP-IPV-Hib | 280 | 278 | 6.18 (6.15–6.21) | 108 | 103 | 6.25 (6.18–6.35) | 0.0054 |
| 12 mo, MMR | 214 | 201 | 12.2 (12.2–12.3) | 127 | 112 | 12.3 (12.2–12.4) | 0.0534 |
| 12 mo, Pneu-C-13 | 188 | 180 | 12.3 (12.2–12.4) | 117 | 105 | 12.3 (12.2–12.4) | 0.0892 |
| 12 mo, Men-C-C | 214 | 202 | 12.3 (12.2–12.4) | 127 | 110 | 12.4 (12.3–12.5) | 0.0072 |
| 15 mo, Var | 175 | 155 | 15.5 (15.3–15.7) | 99 | 76 | 15.7 (15.5–17.3) | 0.0391 |
| 18 mo, DTaP-IPV-Hib | 100 | 93 | 18.4 (18.2–18.6) | 91 | 79 | 18.6 (18.4–18.9) | 0.1093 |
Note: CI = confidence interval; DTaP-IPV-Hib = diphtheria, tetanus, pertussis, polio, Haemophilus influenzae type B; Men-C-C = meningococcal conjugate C; MMR = measles, mumps, rubella; Pneu-C-13 = pneumococcal conjugate 13; Var = varicella.
↵* Calculated using Kaplan–Meier test to assess differences in each of the routine childhood vaccination’s cumulative incidence functions pre-COVID-19 versus during COVID-19.