Table 3:

Risks associated with colonoscopy in FOBT-based screening programs for colorectal cancer

Study location	No. of patients	Ascertainment	FOBT	Polyp removal, %	Follow-up	Event; rate, per 10 000
Study location	No. of patients	Ascertainment	FOBT	Polyp removal, %	Follow-up	All	Perforation	Bleeding	Death
British Columbia (current study)	96 192	Phone call 14 d after colonoscopy	FIT	65	14 d	44	6	26	0.3
Basque, Spain14	39 254	Hospital admission data	FIT	NR	30 d	100	27	62	NR
Denmark15	14 671	Chart review of cases identified through hospital admission data	FIT	55	14 d for bleeding 30 d for other SAEs 90 d for death	61	10	41	0.7
Slovenia16	13 919	Physician and/or patient had option of mailing standardized form to program	FIT	NR	NR	8	8	3	NR
England17	130 831	Mailed questionnaire 30 d after colonoscopy	Guaiac FOBT	53	30 d	142	6	65	0
Alsace, France18	10 277	Phone call 1 d after and mailed questionnaire 30 d after colonoscopy	Guaiac FOBT	49	30 d	243	10	30	0
Gotland, Sweden19	2984	Hospital admission data	Guaiac FOBT	40	30 d	100	10	140	0

Note: FIT = fecal immunochemical test, FOBT = fecal occult blood test, NR = not reported, SAE = serious adverse event.