Table 4:

Barriers, facilitators and perceived impact of initiation of buprenorphine–naloxone in the emergency department

CharacteristicNo. of respondents% of respondents (95% CI)Range across physician groups, %*
Barriers rated as “very significant”
 Lack of adequate training (n = 631)36758.2 (54.3–62.0)14.0–95.2
 Lack of time during clinical encounter (n = 625)34555.2 (51.2–59.1)37.7–79.3
 Lack of physical care space for initiation (n = 601)29849.6 (45.6–53.6)0.0–69.4
 Lack of adequate outpatient follow-up options (n = 598)25242.1 (38.2–46.1)0.0–96.6
 Lack of hospital or ED administrative support (n = 602)22036.5 (32.7–40.4)0.0–89.3
 Limited knowledge of research (n = 607)20734.1 (30.3–37.9)4.7–58.3
Facilitators rated as having “strong impact”
 Availability of specialized staff (n = 630)58993.5 (91.6–95.4)75.0–100.0
 Availability of clinical pathways (n = 624)57391.8 (89.7–94.0)75.0–95.5
 ED BUP initiation is common local practice (n = 628)54186.1 (83.4–88.9)58.8–100.0
 Evidence that BUP decreases overdose mortality (n = 623)53585.9 (83.1–88.6)64.3–100.0
 Timely access to addictions specialist (n = 627)53284.9 (82.0–87.7)64.3–100.0
 Supportive recommendations from professional organization (n = 626)50781.0 (77.9–84.1)53.3–100.0
 Support from ED nursing staff (n = 628)51181.4 (78.3–84.4)58.3–100.0
 Local leaders who recommend ED BUP intitiation (n = 616)45674.0 (70.6–77.5)41.7–96.2
Perceived public health effect of ED BUP initiation§
 Decrease in deaths from opioid overdose (n = 634)50679.8 (76.7–82.9)56.3–96.3
 Decrease in 911 calls for opioid overdose (n = 632)38761.2 (57.4–65.0)36.8–85.0
 Decrease in ED visits for opioid overdose (n = 634)37959.8 (56.0–63.6)36.0–92.3
 Decrease in overall opioid use (n = 632)32451.3 (47.4–55.2)21.7–69.2
  • Note: BUP = buprenorphine–naloxone, CI = confidence interval, ED = emergency department.

  • * Range from the ED group with the lowest positive response rate to the ED group with the highest positive response rate.

  • “Very significant” is a score of at least 4 on a 1–5 scale.

  • “Strong impact” is a score of at least 7 on a 1–10 scale.

  • § “Decrease” is a score of at least 4 on a 1–5 scale.