Table 1:

Components of GRADE-CERQual assessments33

Methodological limitationsThe extent to which problems were identified in the conduct of the primary studies that contributed to the evidence for a review finding
RelevanceThe extent to which the primary studies supporting a review finding are applicable to the context specified in the review question
CoherenceThe extent to which a review finding is based on a pattern of data that is similar across multiple individual studies and/or incorporates (compelling) explanations for any variations across individual studies
Adequacy of dataAn overall determination of the degree of richness and/or scope of the evidence and of the quantity of data supporting a review finding