Analysis* | Province | CGM n = 100 mother/infant dyads | SMBG n = 102 mother/infant dyads | Difference between CGM and SMBG | ||||
---|---|---|---|---|---|---|---|---|
Mean, $ | SEM, $ | Mean, $ | SEM, $ | Mean, $ | SEM, $ | 95% CI†, $ | ||
Primary outcome: total costs excluding glucose monitoring | Ontario | 13 270.25 | 1122.61 | 18 465.21 | 1758.01 | −5194.96 | 2112.07 | −9841 to −1395 |
British Columbia | 13 480.57 | 1154.21 | 18 762.17 | 1786.67 | −5281.60 | 2154.34 | −9964 to −1382 | |
Alberta | 13 294.39 | 1141.15 | 18 674.45 | 1808.81 | −5380.06 | 2165.35 | −10 216 to −1490 | |
Secondary outcome: total costs including glucose monitoring | Ontario | 17 881.01 | 1107.80 | 19 699.65 | 1752.10 | −1818.64 | 2099.14 | −6424 to 1942 |
British Columbia | 18 091.32 | 1139.41 | 19 996.61 | 1780.73 | −1905.29 | 2141.33 | −6588 to 1957 | |
Alberta | 17 905.15 | 1126.42 | 19 908.89 | 1802.87 | −2003.74 | 2152.47 | −6747 to 1844 | |
Ad hoc analysis: maximum costs of CGM to be < SMBG costs | Ontario | 14 546.61 | 1118.35 | 19 699.65 | 1752.10 | −5153.04 | 2102.01 | −9801 to −1372 |
British Columbia | 14 756.92 | 1149.96 | 19 996.61 | 1780.73 | −5239.69 | 2145.74 | −9961 to −1386 | |
Alberta | 14 570.75 | 1136.89 | 19 908.89 | 1802.87 | −5338.14 | 2155.59 | −10 152 to −1473 |
Note: BCA = bias-corrected and accelerated, CGM = continuous glucose monitoring, CI = confidence interval, SEM = standard error of the mean, SMBG = self-monitoring blood glucose.
↵* The primary outcome is the total cost of all services, excluding cost of CGM devices, CGM sensors, glucometers and SMBG strips. The secondary outcome is the total cost of all services, including cost of CGM devices, CGM sensors, glucometers and SMBG strips. The ad hoc analysis estimates the maximum total cost per patient (including cost of CGM devices, CGM sensors, glucometers and SMBG strips) for CGM to remain significantly cheaper than SMBG during type 1 diabetes pregnancy. Negative value favours less costly CGM group.
↵† The 95% CIs were estimated using the BCA method.