Rates of outcome events over time after hospital discharge in the overall cohort
| Outcome | No. (%) of patients | Time; event rate per 100 person-years (95% CI) | ||
|---|---|---|---|---|
| 1 yr | First 30 d | 2–12 mo | ||
| Hemorrhage | 8767 (100.0) | 17.7 (17.4–18.1) | 25.8 (24.8–26.8) | 15.7 (15.3–16.1) |
| Intracranial bleed | 664 (7.6) | 1.3 (1.2–1.4) | 1.2 (1.0–1.4) | 1.4 (1.3–1.5) |
| Upper gastrointestinal bleed | 2392 (27.3) | 4.8 (4.6–5.0) | 7.5 (7.0–8.0) | 4.2 (4.0–4.4) |
| Lower gastrointestinal bleed | 669 (7.6) | 1.4 (1.3–1.5) | 1.9 (1.6–2.2) | 1.2 (1.1–1.3) |
| Other major bleed | 5042 (57.5) | 10.2 (9.9–10.5) | 15.3 (14.5–16.0) | 8.9 (8.6–9.2) |
| Thromboembolic event | 4643 (100.0) | 9.4 (9.1–9.7) | 19.3 (18.4–20.2) | 6.9 (6.6–7.1) |
| Ischemic stroke | 1001 (21.6) | 2.0 (1.9–2.2) | 2.8 (2.5–3.2) | 1.8 (1.7–2.0) |
| Transient ischemic attack | 542 (11.7) | 1.1 (1.0–1.2) | 1.5 (1.2–1.7) | 1.0 (0.9–1.1) |
| Peripheral vascular disease | 789 (17.0) | 1.6 (1.5–1.7) | 1.9 (1.6–2.1) | 1.5 (1.4–1.7) |
| Systemic embolism | 153 (3.3) | 0.3 (0.3–0.4) | 0.6 (0.5–0.8) | 0.2 (0.2–0.3) |
| Pulmonary embolism | 978 (21.1) | 2.0 (1.9–2.1) | 6.4 (5.9–6.9) | 0.9 (0.8–1.0) |
| Deep vein thrombosis | 1180 (25.4) | 2.4 (2.3–2.5) | 6.2 (5.7–6.7) | 1.4 (1.3–1.5) |
Note: CI = confidence interval.