Table 2:

Completeness of reporting scores for each CARE topic and question11

TopicItemQuestionMean COR per item ± SD, %
Title1The words “case report” should be in the title along with what is of greatest interest in this case20 ± 2.5
Keywords2The key elements of this case in 2–5 keywords37 ± 0.0
Abstract3aIntroduction: What is unique about this case? What does it add to the medical literature?41 ± 1.8
3bThe main symptoms of the patient and the important clinical findings31 ± 2.9
3cThe main diagnoses, therapeutics interventions and outcomes38 ± 0.7
3dConclusion: What were the main “take-away” lessons from this case?39 ± 0.4
Introduction4Brief background summary of this case referencing the relevant medical literature72 ± 2.5
Patient information5aDemographic information (e.g., age, gender, ethnicity and occupation)99 ± 0.4
5bMain symptoms of the patient (chief complaints)96 ± 1.4
5cMedical, family and psychosocial history, including comorbidities and relevant genetic information69 ± 1.1
5dRelevant past interventions and their outcomes42 ± 6.9
Clinical findings6Describe the relevant PE findings76 ± 0.7
Timeline7Depict important milestones related to the diagnoses and interventions (table or figure)41 ± 8.3
Diagnostic assessment8aDiagnostic methods (e.g., PE, laboratory testing, imaging and questionnaires)98 ± 0.4
8bDiagnostic challenges (e.g., financial, language and cultural)13 ± 0.4
8cDiagnostic reasoning, including other diagnoses considered76 ± 25.0
8dPrognostic characteristics (e.g., staging in oncology) where applicable14 ± 6.9
Therapeutic intervention9aTypes of intervention (e.g., pharmacologic, surgical, preventive and self-care)84 ± 2.2
9bAdministration of intervention (e.g., dosage, strength and duration)53 ± 9.7
9cChanges in intervention (with rationale)53 ± 11.0
Follow-up and outcomes10aClinician-assessed outcomes and, when appropriate, patient-assessed outcomes71 ± 2.2
10bImportant follow-up test results71 ± 12.0
10cIntervention adherence and tolerability (how was this assessed?)16 ± 14.0
10dAdverse and unanticipated events22 ± 10.4
Discussion11aDiscussion of the strengths and limitations in the management of this case45 ± 0.7
11bDiscussion of the relevant medical literature82 ± 0.7
11cThe rationale for conclusions (including assessment of possible causes)83 ± 4.3
11dThe main “take-away” lessons of this case report88 ± 4.7
Patient perspective12Did the patient share his or her perspective or experience? (include when appropriate)1.8 ± 0.4
Informed consent13Did the patient give informed consent? Please provide if requested33 ± 1.4
Additional information14Acknowledgement section; competing interests; institutional review board approval when required84 ± 5.1
  • Note: CARE = Case Report statement and checklist, COR = completeness of reporting, PE = physical examination, SD = standard deviation.