Results comparing the addition of a smoking cessation intervention to a low-dose computed tomography screening program for lung cancer versus lung cancer screening program alone
| Variable | Result |
|---|---|
| Outcome per 1000 people eligible for smoking cessation intervention* | |
| No. of lung cancer cases prevented | 12 |
| No. of life-years gained | 200 |
| Outcome per 1000 people eligible for smoking cessation intervention* discounted at 1.5% per year | |
| Life-years gained | 130 |
| QALYs gained | 98 |
| Smoking cessation intervention costs, $ | 2.8 million |
| Incremental cost of lung cancer treatments, $ | −600 000 |
| Incremental total direct health care costs, $† | 2.2 million |
| Incremental cost per QALY gained, $ | 22 200 |
Note: QALY = quality-adjusted life-year.
↵* Based on base-case screening program that assumes annual screening of people aged 55–74 years with 30 pack-year or more smoking history, 60% recruitment rate phased in over 10 years and rescreening adherence rate of 70%; base-case smoking cessation intervention assumes 10 cessation attempts with 2.5% quit rate per attempt at a cost of $622 per attempt.
↵† Includes costs of smoking cessation intervention and lung cancer screening, and direct health care costs of treating lung cancer.