Table 2:

Availability of pediatric information in drug monographs by therapeutic class and indications

Therapeutic classMonographs presenting pediatric indications, by age groupIndications of drugs approved for adults with no pediatric information*
12ā€“17 yr6ā€“11 yr2ā€“5 yr28 dā€“1 yrNeonatesPretermAge not specifiedTotal
Allergy or immunology877400110Crohn disease, plaque psoriasis, seasonal allergic rhinitis or conjunctivitis, systemic lupus erythematosus, ulcerative colitis
Anesthesia or analgesia00000000Intensive care unit sedation, severe pain, topical analgesia
Cardiology22000002Arrhythmia, atrial fibrillation, dyslipidemia, familial hypercholesteremia, heart failure, hypertension, perioperative hypertension, pulmonary arterial hypertension
Dermatology00000000Actinic keratosis, basal cell carcinoma, eczema, rosacea
Diagnostic imaging11111001Hepatic or cardiac vascular imaging
Endocrine or metabolic101010820010Cushing syndrome, diabetes, lipodystrophy
Gastrointestinal32211003Chronic idiopathic constipation, cirrhosis, irritable bowel syndrome, opioid-induced constipation, nausea or vomiting
Hematology877310311Anemia, embolism treatment and prevention, hemostasis, stroke prevention, thrombocytopenic purpura, polycythemia vera
Infectious disease171310711018Clostridium difficile infection, hepatitis C, human immunodeficiency virus, intra-abdominal infections, invasive systemic fungal infections, methicillin-resistant Staphylococcus aureus infections, onychomycosis, pneumonia, skin infections
Neurology32200014Parkinson disease, dementia, partial-onset seizures, restless leg syndrome, relapsing remitting multiple sclerosis, reversal of neuromuscular blockade
Obstetrics or gynecology10000001Uterine fibroids, vasomotor symptoms associated with menopause
Oncology44320014Acute lymphoblastic leukemia, breast cancer, Castleman disease, chronic lymphocytic leukemia, chronic myelogenous leukemia, colorectal cancer, gastric cancer, hepatocellular carcinoma, leukemia, lymphoma, melanoma, multiple myeloma, non-small cell lung carcinoma, ovarian cancer, renal cell carcinoma, soft tissue sarcoma, prostate cancer
Ophthalmology22210002Actinic keratosis, age-related macular degeneration, ocular pain, open angle glaucoma, postoperative inflammation
Psychiatry20000002Anxiety, maintenance of alcohol abstinence, antipsychotics, major depressive disorder
Pulmonology53200005Chronic obstructive pulmonary disease, chronic bronchitis, emphysema, asthma, idiopathic pulmonary fibrosis
Rheumatology11100001Gout, psoriatic arthritis, rheumatoid arthritis
Urology00000000Benign prostatic hyperplasia, overactive bladder
  • * For no. of drug monographs that do not present pediatric indications (per therapeutic class), see Table 1.