Annualized thiamine prescribing before and after changes to the computerized provider order entry system, stratified by service
| Variable; prescribing service | Before intervention | After intervention | Percentage change | RR (95% CI) | |||
|---|---|---|---|---|---|---|---|
| Total no. of prescriptions | % parenteral | Total no. of prescriptions | % parenteral | Total no. of prescriptions | % parenteral | ||
| Annualized no. of prescriptions for thiamine | |||||||
| Emergency department | 675 | 62.7 | 1592 | 87.9 | 135.8 | 40.2 | 1.40 (1.34 to 1.46) |
| Intensive care unit | 181 | 77.3 | 747 | 98.9 | 313.7 | 28.0 | 1.28 (1.21 to 1.35) |
| Medical subspecialty | 309 | 49.9 | 82 | 91.8 | −73.5 | 83.9 | 1.84 (1.69 to 2.01) |
| Medicine | 968 | 46.2 | 752 | 94.5 | −22.3 | 104.7 | 2.05 (1.95 to 2.15) |
| Neurology | 90 | 70.4 | 56 | 93.7 | −37.9 | 33.1 | 1.33 (1.20 to 1.47) |
| Psychiatry | 44 | 26.1 | 20 | 77.9 | −55.1 | 198.2 | 2.98 (2.05 to 4.33) |
| Surgery | 787 | 57.8 | 471 | 95.1 | −40.2 | 64.7 | 1.65 (1.78 to 1.72) |
| Annualized no. of first prescriptions for thiamine | |||||||
| Emergency department | 320 | 64.5 | 1394 | 88.0 | 335.6 | 36.3 | 1.36 (1.29 to 1.45) |
| Intensive care unit | 97 | 72.5 | 369 | 99.1 | 282.1 | 36.7 | 1.37 (1.25 to 1.49) |
| Medical subspecialty | 145 | 47.2 | 40 | 90.4 | −72.7 | 91.4 | 1.91 (1.68 to 2.19) |
| Medicine | 505 | 45.6 | 251 | 95.0 | −50.3 | 108.4 | 2.08 (1.95 to 2.23) |
| Neurology | 44 | 77.3 | 21 | 97.2 | −53.1 | 25.8 | 1.26 (1.12 to 1.42) |
| Psychiatry | 20 | 25.0 | 11 | 84.6 | −43.3 | 238.5 | 3.38 (1.95 to 5.89) |
| Surgery | 324 | 57.5 | 251 | 96.4 | −22.5 | 67.7 | 1.68 (1.57 to 1.79) |
| Annualized no. of doses of thiamine prescribed | |||||||
| Emergency department | 1386 | 31.1 | 1683 | 88.5 | 21.5 | 184.5 | 2.84 (2.69 to 3.01) |
| Intensive care unit | 482 | 70.1 | 1340 | 97.9 | 178.0 | 39.5 | 1.39 (1.34 to 1.45) |
| Medical subspecialty | 969 | 40.6 | 189 | 93.2 | −80.5 | 129.6 | 2.30 (2.17 to 2.43) |
| Medicine | 2457 | 43.3 | 1810 | 93.0 | −26.3 | 114.6 | 2.15 (2.08 to 2.22) |
| Neurology | 248 | 67.1 | 129 | 94.1 | −48.1 | 40.2 | 1.40 (1.31 to 1.50) |
| Psychiatry | 167 | 15.9 | 44 | 71.9 | −73.3 | 351.7 | 4.52 (3.46 to 5.89) |
| Surgery | 2266 | 48.8 | 870 | 93.8 | −61.6 | 92.0 | 1.92 (1.86 to 1.98) |
Note: CI = confidence interval, RR = relative risk of parenteral prescribing after the intervention.