Table 4:

Ten most costly and 10 most commonly reimbursed medications, by cost category of beneficiaries

Rank	Beneficiaries with very high drug-costs		High–drug-cost beneficiaries		Other beneficiaries

	Drug name	No. of users	Drug name	No. of users	Drug name	No. of users
Total spending

1	Infliximab^*	331 002 170	Ranibizumab^*	149 319 608	Salmeterol/ fluticasone	110 037 629

2	Sofosbuvir/ledipasvir^†	270 669 622	Aflibercept	122 412 063	Atorvastatin	108 457 147

3	Adalimumab^*	145 652 072	Adalimumab^*	82 784 426	Perindopril	91 622 949

4	Lenalidomide	118 550 630	Paliperidone	62 288 410	Rosuvastatin	86 933 263

5	Etanercept^*	86 154 466	Etanercept	50 613 266	Metformin/ sitagliptin	83 201 111

6	Sofosbuvir^†	74 950 373	Insulin glargine	38 740 800	Sitagliptin	76 710 532

7	Ranibizumab^*	65 440 527	Infliximab^*	37 537 419	Methadone	76 477 878

8	Aflibercept	52 468 572	Hydromorphone	36 425 150	Rivaroxaban	75 651 662

9	Eculizumab^*	37 516 433	Aripiprazole	34 064 003	Insulin glargine	74 519 810

10	Dasabuvir/ombitasvir/ paritaprevir/ritonavir^†	36 048 600	Methadone	28 115 644	Pantoprazole	72 636 566

Total use

1	Pantoprazole	10 090	Pantoprazole	56 988	Rosuvastatin	894 699

2	Infliximab^*	9645	Salbutamol	55 470	Atorvastatin	785 322

3	Salbutamol	9104	Rosuvastatin	44,517	Pantoprazole	733 233

4	Codeine/ acetaminophen	7524	Atorvastatin	43 747	Amoxicillin	723 256

5	Prednisone	7308	Metformin	43 583	Levothyroxine	705 881

6	Amoxicillin	7274	Furosemide	41 962	Salbutamol	646 392

7	Rosuvastatin	7072	Amlodipine	36 877	Amlodipine	632 970

8	Adalimumab^*	6549	Levothyroxine	36 700	Metformin	599 120

9	Methotrexate	6277	Amoxicillin	34 237	Codeine/ acetaminophen	531 586

10	Levothyroxine	6228	Codeine/ acetaminophen	34 045	Ramipril	473 130