Summary of recommendations for acetylsalicylic acid use in primary prevention of cardiovascular disease
| Organization, year | Recommendation |
|---|---|
| American College of Cardiology/American Heart Association, 20197 | Consider for adults aged 40–70 yr at high risk |
| Hypertension Canada, 201819 | Consider for hypertensive adults aged ≥ 50 yr |
| Canadian Diabetes Association, 201823 | Do not use routinely, but may be used in presence of additional cardiovascular risk factors other than diabetes |
| US Preventive Services Task Force, 20168 | Initiate for adults aged 50–59 yr with a 10-year CVD risk ≥ 10%; individualize decision for adults aged 60–69 yr with a 10-year CVD risk ≥ 10% |
| Sixth Joint Task Force of the European Society of Cardiology and Other Societies, 201620 | Do not initiate |
| US Food and Drug Administration, 201421 | Do not initiate |
| American Heart Association/American Stroke Association, 201422 | ASA use is reasonable if 10-year CVD risk is ≥ 10% |
| American College of Chest Physicians, 201224 | Suggested for adults aged ≥ 50 yr |
| Canadian Cardiovascular Society, 201125 | Consider if high vascular risk |
| US Preventive Services Task Force, 200917 | Encourage men aged 45–79 yr and women aged 55–79 yr to use ASA when potential CVD benefit outweighs potential harm (based on 10-year CVD risk) |
Note: ASA = acetylsalicylic acid, CVD = cardiovascular disease.