Indicators of potentially inappropriate use of benzodiazepine receptor agonists (BZRAs) at the patient level according to age and sex
| Overall n = 372 870 | Age category, yr, no. (%)* | Sex, no. (%)* | ||||
|---|---|---|---|---|---|---|
| 10–19 n = 6550 | 20–64 n = 260 600 | ≥ 65 n = 105 720 | Female n = 234 140 | Male n = 138 725 | ||
| Maximum period of consecutive use, d | ||||||
| Mean ± SD | 90 ± 95 | 31 ± 48 | 77 ± 89 | 126 ± 102 | 91 ± 96 | 90 ± 94 |
| ≤ 30 | 106 603 (28.6) | 4400 (67.2) | 86 863 (33.3) | 15 340 (14.5) | 67 663 (28.9) | 38 937 (28.1) |
| 31–90 | 124 090 (33.3) | 1555 (23.7) | 93 894 (36.0) | 28 641 (27.1) | 76 949 (32.9) | 47 140 (34.0) |
| 91–120 | 44 575 (12.0) | 228 (3.5) | 25 073 (9.6) | 19 274 (18.2) | 28 199 (12.0) | 16 376 (11.8) |
| ≥ 121 | 97 602 (26.2) | 267 (5.6) | 54 770 (21.0) | 42 465 (40.2) | 61 329 (26.2) | 36 272 (26.2) |
| Maximum no. of unique ingredients used concurrently | ||||||
| 1 | 310 075 (83.2) | 6040 (92.2) | 214 385 (82.3) | 89 650 (84.8) | 193 179 (82.5) | 116 891 (84.3) |
| 2 | 55 072 (14.8) | 482 (7.4) | 39 899 (15.3) | 14 691 (13.9) | 35 847 (15.3) | 19 225 (13.9) |
| ≥ 3 | 7723 (2.1) | 28 (0.4) | 6316 (2.4) | 1379 (1.3) | 5115 (2.2) | 2609 (1.9) |
| No. of distinct prescribers | ||||||
| Mean ± SD | 1.5 ± 1.0 | 1.2 ± 0.6 | 1.5 ± 1.1 | 1.4 ± 0.8 | 1.5 ± 1.0 | 1.5 ± 10 |
| 1 | 265 620 (71.2) | 5413 (82.6) | 184 864 (70.9) | 75 343 (71.3) | 167 950 (71.7) | 97 666 (70.4) |
| 2 | 70 300 (18.9) | 847 (12.9) | 47 981 (18.4) | 21 472 (20.3) | 43 810 (18.7) | 26 489 (19.1) |
| 3 | 22 210 (6.0) | 193 (3.0) | 15 784 (6.1) | 6233 (5.9) | 13 645 (5.8) | 8656 (6.2) |
| ≥ 4 | 14 740 (4.0) | 97 (1.5) | 11 971 (4.6) | 267 (2.5) | 8735 (3.7) | 6005 (4.3) |
Note: SD = standard deviation.
↵* Except where indicated otherwise.