Table 4:

Total number of QREs, number of harm QREs and proportion of harm QREs for each type

TypeNo. (%) of QREsNo. (%) of harm QREs*Proportion of harm QREs*, %
Incorrect dose or frequency25 089 (25.6)254 (27.4)1.0
Incorrect quantity19 619 (20.0)19 (2.0)0.1
Incorrect drug13 951 (14.2)185 (19.9)1.3
Incorrect strength or concentration10 508 (10.7)187 (20.2)1.8
Incorrect prescriber8454 (8.6)0 (0)0.0
Incorrect patient5685 (5.8)32 (3.4)0.6
Incorrect duration of treatment5048 (5.1)18 (1.9)0.4
Incorrect dosage form or formulation (including not splitting tablets as per patient’s request)3281 (3.3)32 (3.4)1.0
Omitted medication or dose1919 (2.0)58 (6.233.0
Incorrect route of administration1121 (1.1)7 (0.8)0.6
Incorrect storage857 (0.9)3 (0.3)0.4
Incorrect third-party billing803 (0.8)1 (0.1)0.1
Drug therapy problem — drug–drug/OTC/natural health product interaction506 (0.5)19 (2.0)3.8
Drug therapy problem — documented allergy447 (0.5)31 (3.3)6.9
Drug therapy problem — contraindication356 (0.4)12 (1.3)3.4
Expired medication191 (0.2)9 (1.0)4.7
Drug therapy problem — adverse drug reaction188 (0.2)56 (6.0)29.8
Drug therapy problem — drug–disease interaction63 (0.1)3 (0.3)4.8
Drug therapy problem — drug–food interaction11 (0.0)2 (0.2)18.2
Total98 097 (100)928 (100)
  • Note: OTC = over the counter, QRE = quality-related event.

  • * Harm QREs are associated with a patient outcome of mild harm, moderate harm, severe harm or death (Table 2).