Characteristics of the overall cohort with thickness information, and stratified by ulceration status
| Characteristic | Overall n = 8042 | Ulceration absent n = 6581 | Ulceration present n = 1461 |
|---|---|---|---|
| Patient factors | |||
| Sex, % | |||
| Male | 53.3 | 51.1 | 63.1 |
| Female | 46.7 | 48.9 | 36.9 |
| Median age, yr (mean) | 62 (61.52) | 61 (60.28) | 69 (67.09) |
| Age group, % | |||
| 20–45 yr | 17.2 | 18.7 | 10.2 |
| 46–55 yr | 18.5 | 19.5 | 13.6 |
| 56–65 yr | 21.4 | 22.0 | 18.6 |
| 66–75 yr | 20.1 | 19.7 | 21.9 |
| 76–85 yr | 17.5 | 15.9 | 24.9 |
| >85 yr | 5.4 | 4.2 | 10.8 |
| Material deprivation, % | |||
| Least deprived | 27.1 | 27.8 | 24.0 |
| Quintile 2 | 23.8 | 23.6 | 24.9 |
| Quintile 3 | 19.5 | 19.2 | 20.8 |
| Quintile 4 | 14.2 | 13.8 | 16.0 |
| Most deprived | 9.0 | 8.4 | 11.8 |
| Data missing | 6.3 | 7.2 | 2.5 |
| Health-system factors | |||
| LHIN, % | |||
| LHIN A | 8.3 | 8.6 | 7.0 |
| LHIN B | 7.7 | 8.1 | 5.8 |
| LHIN C | 9.3 | 9.5 | 8.7 |
| LHIN D | 4.9 | 4.7 | 6.1 |
| LHIN E | 10.6 | 11.0 | 8.9 |
| LHIN F | 6.6 | 6.7 | 6.3 |
| LHIN G | 5.8 | 5.8 | 6.0 |
| LHIN H | 12.2 | 12.1 | 12.6 |
| LHIN I | 6.5 | 6.3 | 7.4 |
| LHIN J | 1.3 | * | * |
| LHIN K | 3.3 | 3.3 | 3.4 |
| LHIN L | 13.3 | 12.6 | 16.2 |
| LHIN M | 5.7 | 5.6 | 5.8 |
| LHIN N | 4.4 | * | * |
| Median rurality† (mean) | 5.0 (13.49) | 5.0 (13.48) | 5.0 (13.52) |
| Rural (≥40), % | 10.2 | 10.0 | 10.6 |
| Non-major urban (9.01–39), % | 26.2 | 26.3 | 26.2 |
| Major urban (0–9), % | 57.4 | 56.6 | 60.9 |
| Data missing, % | 6.3 | 7.1 | 2.4 |
| Disease factors | |||
| Median Breslow thickness (mean), mm | 0.87 (2.02) | 0.70 (1.28) | 3.86 (5.34) |
| T1 (≤1.0), % | 55.7 | 66.8 | 6.0 |
| T2 (> 1, ≤ 2.0), % | 18.6 | 19.1 | 16.0 |
| T3 (> 2.0, ≤ 4.0), % | 13.1 | 9.0 | 31.3 |
| T4 (>4.0), % | 12.7 | 5.1 | 46.8 |
| Histological subtype, % | |||
| Superficial spreading | 41.1 | 45.0 | 23.7 |
| Lentigo maligna | 8.1 | 9.3 | 2.7 |
| Acral lentiginous | 1.6 | 1.1 | 3.9 |
| Nodular | 13.2 | 7.3 | 39.8 |
| NOS | 31.8 | 33.7 | 23.4 |
| Other | 4.1 | 3.6 | 6.4 |
| Body site, % | |||
| Extremities | 46.2 | 46.5 | 45.0 |
| Face | 12.4 | 12.6 | 11.7 |
| Head and neck | 5.7 | 5.3 | 7.7 |
| Trunk | 32.2 | 32.5 | 31.1 |
| Unspecified | 3.5 | 3.2 | 4.5 |
| Presence of ulceration, % | |||
| Present | 18.2 | – | – |
| Absent | 81.8 | – | – |
| Lymph node involvement, % | |||
| Present | 10.0 | 5.8 | 28.8 |
| Absent | 90.0 | 94.2 | 71.2 |
| Distant metastases, % | |||
| Present | 1.2 | 0.8 | 3.2 |
| Absent | 98.8 | 99.2 | 96.9 |