Table 1:

Characteristics of immigrant and refugee children referred to The Hospital for Sick Children for tuberculosis medical surveillance, November 2012 to June 2016

CharacteristicNo. (%) of children
No IGRA done
n = 40
IGRA result negative
n = 152
IGRA result positive
n = 24
Total
n = 216
Sex
Male22 (45)86 (43.4)10 (58)118 (54.6)
Female18 (55)66 (56.6)14 (42)98 (45.4)
Age, yr
≤ 52 (5)21 (13.8)0 (0)23 (10.6)
6–1024 (60)70 (46.0)10 (42)104 (48.1)
11–1614 (35)61 (40.1)14 (58)89 (41.2)
Country of birth
Philippines32 (80)108 (71.0)17 (71)157 (72.7)
India*3 (8)32 (21.0)4 (17)39 (18.0)
Israel2 (5)3 (2.0)0 (0)5 (2.3)
Saudi Arabia0 (0)2 (1.3)1 (4)3 (1.4)
Russia0 (0)2 (1.3)0 (0)2 (0.9)
Nepal0 (0)2 (1.3)0 (0)2 (0.9)
Other3 (8)3 (2.0)2 (8)8 (3.7)
Reason for medical surveillance referral
History of prior treatment for tuberculosis36 (90)110 (72.4)20 (83)166 (76.8)
Refugee resettlement program (automatic referral)0 (0)31 (20.4)3 (12)34 (15.7)
Possible tuberculosis contact1 (2)3 (2.0)0 (0)4 (1.8)
Positive tuberculin skin test result on immigration2 (5)3 (2.0)1 (4)6 (2.3)
Abnormal chest radiograph on immigration0 (0)3 (2.0)0 (0)3 (1.4)
Other1 (2)2 (1.3)0 (0)3 (0.9)
Prior diagnosis
Primary complex tuberculosis31 (78)101 (66.4)18 (75)150 (69.4)
Tuberculosis disease (site specific)4 (10)6 (3.9)1 (4)11 (5.1)
Pulmonary tuberculosis2 (5)6 (3.9)1 (4)9 (4.2)
Lymph node tuberculosis2 (5)0 (0.0)0 (0)2 (0.9)
Latent tuberculosis infection1 (2)2 (1.3)1 (4)4 (1.8)
No prior diagnosis0 (0)37 (24.3)3 (12)40 (18.5)
Symptoms in country of origin that led to diagnosis of tuberculosis disease
None13 (32)56 (36.8)9 (38)78 (36.1)
Unknown8 (20)30 (19.7)7 (29)45 (20.8)
Known19 (48)66 (43.4)8 (33)93 (43.0)
 Cough17 (42)57 (37.5)6 (25)80 (37.0)
 Fever/headache9 (22)25 (16.4)2 (8)36 (16.7)
 Weight loss/poor appetite2 (5)17 (11.2)2 (8)21 (9.7)
 Lymphadenopathy3 (8)5 (3.3)1 (4)9 (4.2)
 Cold- or “flu”-like symptoms1 (2)6 (3.9)2 (8)9 (4.2)
 Abdominal pain1 (2)0 (0.0)0 (0)1 (0.5)
 Vomiting1 (2)0 (0.0)0 (0)1 (0.5)
 Diarrhea1 (2)0 (0.0)0 (0)1 (0.5)
  • Note: IGRA = interferon-γ release assay.

  • * Thirty-seven children born in India were federally sponsored refugees of Tibetan descent.

  • Nine children born in Israel, Saudi Arabia, Italy or Lebanon had migrated to the Philippines before migration to Canada.