Table 1:

Summary of key model parameters over a 4-month period

Variable/stateValue (range)Source
Transition probability, %
Rate of development of low-risk diabetic foot ulcer0.3 (0.3–0.41)Lavery et al.39
Rate of development of moderate-risk diabetic foot ulcer0.45 (0.45–2.18)Lavery et al.39
Rate of development of recurrent diabetic foot ulcer11.21 (7.17–15.66)Armstrong et al.,40 Dubský et al.41
Healing rate for low-risk diabetic foot ulcer45.71Prompers et al.42
Healing rate for moderate-risk diabetic foot ulcer32.32Prompers et al.42
Healing rate for recurrent diabetic foot ulcer11.51Örneholm et al.43
Amputation rate for low-risk diabetic foot ulcer0.67 (0.3–0.77)Lavery et al.,39 Prompers et al.,42 Moulik et al.44
Amputation rate for moderate-risk diabetic foot ulcer2.74 (0.063–8.54)Lavery et al.,39 Prompers et al.,42 Morbach et al.,45 Oyibo et al.46
Amputation rate for recurrent diabetic foot ulcer3.45 (0.68–3.45)Lavery et al.,39 Örneholm et al.43
Mortality rate for low-risk diabetic foot ulcer1.17 (1.01–2.73)Prompers et al.,42 Morbach et al.45
Mortality rate for moderate-risk diabetic foot ulcer3.26 (3.26–8.07)Prompers et al.,42 Morbach et al.45
Mortality rate for recurrent diabetic foot ulcer3.26 (3.26–8.07)Prompers et al.,42 Örneholm et al.,43 Morbach et al.45
Mortality rate for amputationSee Supplementary Figure A3, Appendix 1Aulivola et al.47
Utility/cost*
No ulcer0.7850 (0.681–0.889)Beaudet et al.48
Active diabetic foot ulcer0.615 (0.578–0.652)Beaudet et al.48
Healed diabetic foot ulcer0.680Redekop et al.49
Amputation0.505 (0.396–0.615)Beaudet et al.48
Initial screen, $60.00Ontario Ministry of Health and Long-Term Care50
At low risk for diabetic foot ulcer, $67.80Ontario Ministry of Health and Long-Term Care50
At moderate risk for diabetic foot ulcer, $85.87Ontario Ministry of Health and Long-Term Care50
Diabetic foot ulcer, $2395.75Ontario Ministry of Health and Long-Term Care,50 Canadian Institute for Health Information51
Amputation, $16 752.15Ontario Ministry of Health and Long-Term Care,50 Canadian Institute for Health Information51
Healed amputation, $78.40Ontario Ministry of Health and Long-Term Care,50 Canadian Institute for Health Information51
Healed diabetic foot ulcer, $135.60Ontario Ministry of Health and Long-Term Care50
Telemedicine device, $20.00Fasterholdt et al.52
Telemedicine service, $14.65Ontario Telemedicine Network53
  • * 2015 Canadian dollars.