Table 1:

Estimated frequency of events per 1000 eligible patients over lifetime among patients treated or not treated with evolocumab in addition to a statin

EventUntreated patientsNo. of events Treated patientsEvents prevented
Recurrent myocardial infarction460.8404.956.0
Cardiovascular death416.7361.555.2
New or recurrent myocardial infarction484.2429.954.3
Cardiovascular death, myocardial infarction (new or recurrent) or stroke752.7700.751.9
Stroke or transient ischemic attack354.2324.929.3
Fatal myocardial infarction149.2120.129.2
Stroke293.8266.327.5
Sudden death87.570.117.3
Stroke death96.483.812.5
Transient ischemic attack92.885.57.3
Newly diagnosed diabetes332.5327.35.2
New myocardial infarction52.149.22.9
Angina pectoris41.538.72.8
Coronary insufficiency9.79.10.6
Congestive heart failure death84.988.5−3.6
Congestive heart failure107.5111.2−3.7
Other death579.2634.6−55.4