| Test; variable | No. (%) of people* | p value | |
|---|---|---|---|
| Specialist consultation n = 390 | No specialist consultation n = 824 | ||
| ALT | 389 (99.7) | 803 (97.4) | 0.01 |
| Median level (IQR), U/L | 23.5 (17-36) | 22 (16-33) | 0.02 |
| Level ≥ 2 times upper limit of normal† | 54 (13.9) | 63 (7.8) | < 0.01 |
| HBV DNA | 286 (73.3) | 396 (48.0) | < 0.01 |
| Median level (IQR), logIU/mL | 2.4 (1.1-3.5) | 2.5 (1.5-3.4) | 0.4 |
| < 1 logIUmL | 79 (27.6) | 75 (18.9) | < 0.01 |
| ≥ 3.3 logIUmL† | 77 (26.9) | 103 (26.0) | 0.8 |
| HBeAg | 273 (70.0) | 357 (43.3) | < 0.01 |
| Negative result | 231 (84.6) | 317 (88.8) | 0.2 |
| HBeAb | 60 (15.4) | 85 (10.3) | 0.01 |
| Positive result | 45 (75.0) | 66 (77.6) | 0.8 |
| HBV DNA testing in people with ALT level ≥ 2 times upper limit of normal | 37 (68.5) | 31 (49.2) | 0.04 |
| Median level (IQR), logIU/mL | 2.8 (1.5-4.9) | 4.1 (1.4-5.8) | 0.5 |
| < 1 logIUmL | 7 (18.9) | 6 (19.4) | 1.0 |
| ≥ 3.3 logIUmL | 14 (37.8) | 17 (54.8) | 0.2 |
| HBV DNA testing in HBeAb-negative people | 186 (80.5) | 247 (77.9) | 0.5 |
| Median level (IQR), logIU/mL | 2.5 (1.2-3.3) | 2.5 (1.6-3.3) | 0.3 |
| < 1 logIUmL | 51 (27.4) | 39 (15.8) | < 0.01 |
| ≥ 3.3 logIUmL | 46 (24.7) | 60 (24.3) | 0.9 |
Note: ALT = alanine aminotransferase, HBV = hepatitis B virus, HBeAb = HBV e antibody, HBeAg = HBV e antigen, IQR = interquartile range.
*Except where noted otherwise.
†Clinically significant level.