Table 2: Treatment efficacy (sustained virological response) used in the model
DescriptionBaseline* or RRLower limit
(95% CrI)		Upper limit
(95% CrI)
Genotype 1: treatment-naive
Noncirrhosis
   Reference baseline PR480.4913*0.43590.5456
   SOF24 + RBV241.6341.2881.899
   SIM12 + SOF121.8020.80042.186
   SOF12 + LDV121.9781.782.225
   PAR/RIT12 + OMB12 + DAS121.9321.3372.211
   PAR/RIT12 + OMB12 + DAS12 + RBV121.9441.7482.18
   T12 PR24-48 RGT q81.5551.3121.767
   SOF12 + PR121.7691.2782.065
   SOF12 + PR24-48 RGT1.7271.2452.055
   SIM12 + PR24-48 RGT1.5891.4111.784
   B24 PR28-48 RGT1.5381.2681.777
   SIM12 + SOF12 + RBV121.7660.86012.176
   DCV12 + SOF121.8981.2762.212
Cirrhosis
   Reference baseline PR480.3958*0.30920.4906
   SOF24 + RBV241.7570.62072.571
   SIM12 + SOF122.1750.93472.949
   SOF12 + LDV122.4081.8933.089
   T12 PR24-48 RGT q81.430.63682.195
   SOF12 + PR122.0381.1252.749
   SIM12 + PR24-48 RGT1.6951.0572.387
   B24 PR28-48 RGT0.64560.16091.653
Genotype 1: treatment-experienced
Noncirrhosis
   Reference baseline PR480.2571*0.22420.292
   SIM12 + SOF121.0230.049153.635
   SOF12 + LDV123.5642.9924.151
   PAR/RIT12 + OMB12 + DAS123.7533.2044.329
   PAR/RIT12 + OMB12 + DAS12 + RBV123.8183.3454.387
   T12 PR48 q83.0382.4053.633
   SOF12 + PR123.0972.2763.768
   SIM12 + PR24-48 RGT2.5871.7573.207
   SIM12 + PR483.0452.1523.718
   SIM12 + SOF12 + RBV122.3540.22713.878
   B32 PR36-48 RGT2.5471.6923.328
Cirrhosis
   Reference baseline PR480.1691*0.11650.2334
   SIM12 + SOF124.6651.7967.161
   SOF24 + LDV244.5031.6037.215
   SOF12 + LDV12 + RBV124.6262.9317.005
   T12 PR48 q83.0271.3615.425
   SOF12 + PR122.9440.31616.236
   SIM12 + PR24-48 RGT3.5631.6086.091
   SIM12 + PR482.7090.89185.319
   B32 PR36-48 RGT2.5210.71325.623
Genotype 2: treatment-naive
Noncirrhosis
   SOF12 + RBV121.161.0831.244
   SOF12 PR121.1480.47621.266
   Reference baseline PR240.8191*0.76870.8619
   Cirrhosis
   SOF12 + RBV121.3751.0261.791
   Reference baseline PR240.6209*0.49660.7344
Genotype 2: treatment-experienced
Noncirrhosis
   Reference baseline SOF12 + RBV120.9549*0.90710.9829
   SOF12 + PR121.0060.89141.071
Cirrhosis
   Reference baseline SOF12 + RBV120.7331*0.5790.8554
   SOF12 + PR121.2860.98651.643
   SOF16 + RBV161.0520.71231.414
Genotype 3: treatment-naive
Noncirrhosis
   Reference baseline PR480.7051*0.63930.765
   SOF24 + RBV241.3181.1771.47
   DCV12 + SOF121.3751.2331.525
Cirrhosis
   Reference baseline PR480.6021*0.55840.6441
   SOF24 + RBV241.5091.1421.702
Genotype 3: treatment-experienced
Noncirrhosis
   Reference baseline PR480.6082*0.57860.6374
   SOF24 + RBV241.4671.3151.591
   SOF12 + PR121.3840.87981.62
   DCV12 + SOF121.5441.3061.667
Cirrhosis
   Reference baseline PR480.4777*0.43820.5174
   SOF24 + RBV241.4651.1391.789
   SOF12 + PR121.7311.092.086
Genotype 4: treatment-naive
Noncirrhosis
   Reference baseline PR480.6502*0.63350.6668
   SOF24 + RBV241.2680.8951.465
   SOF12 + PR121.4821.2691.552
Cirrhosis
   Reference baseline PR480.3804*0.35670.4052
   SOF24 + RBV242.271.3612.65
Genotype 4: treatment-experienced
Noncirrhosis
   Reference baseline SOF12 + RBV120.6345*0.44830.7983
   SOF24 + RBV241.280.68141.905
Cirrhosis
   Reference baseline SOF12 + RBV120.5628*0.24220.8484
   SOF24 + RBV241.4690.57283.505

Note: Probability distribution based on network meta-analysis.15 For descriptions or treatment regimens, see Table 1. CrI = credible interval, RR = relative risk.

*Baseline probability.