Table 2: Pathology results for the 1555 participants who underwent colonoscopy after a positive fecal immunochemical test result
Pathology result*No. of casesPositive predictive value, % (95% CI)Detection rate per 1000 screened
Colorectal cancer764.9 (3.8-6.0)3.5
Precancerous polyp†88857.0 (54.7-59.6)41.2
   High-risk polyp54335.0 (32.5-37.2)25.2
   Low-risk polyp34522.2 (20.1-24.3)16.0
Any neoplasm 96462.0 (59.6-64.4)44.8

Note: CI = confidence interval.

*Pathology results were classified by the most serious lesion identified in each participant.

†This row contains the combined results for high-risk and low-risk precancerous polyps. High-risk precancerous polyps were defined according to published guidelines10 as tubular adenomas 10 mm in size, tubulovillous or villous adenomas, adenomas with high-grade dysplasia, sessile serrated adenomas, traditional serrated adenomas, and multiple ( 3) tubular adenomas less than 10 mm in size. Low-risk precancerous polyps were defined as 1 or 2 tubular adenomas less than 10 mm in size.