Table 1: Relative risks of cancers associated with use of oral contraceptives and hormone therapy

Exposure	Cancer site	Detailed exposure	Risk estimate (95% CI)	Source
Oral contraceptives	Breast	Ever use	1.08 (1.00-1.17)	Gierisch et al. 2013²
	Endometrium	Ever use	0.57 (0.43-0.77)	Gierisch et al. 2013²
	Ovary	Ever use	0.73 (0.66-0.81)	Havrilesky et al. 2013³
Hormone therapy*	Breast	Ever use	1.39 (1.12-1.72)	Shah et al. 2005⁵
	Breast	Current use	1.66 (1.58-1.75)	Beral 2003²⁷
	Endometrium	Ever use	0.78 (0.72-0.86)	Brinton et al. 2014⁶
	Endometrium	Current use	0.75 (0.58-0.97)	Beral et al. 2005²⁴
	Ovary	Ever use	1.20 (1.15-1.26)	Beral et al. 2015⁷
	Ovary	Current use	1.41 (1.32-1.50)	Beral et al. 2015⁷

Note: CI = confidence interval.

*Continuous estrogen-progestin combined hormone therapy (progestins were included in the therapy for > 25 d/mo).